Peptide-based vaccines for tuberculosis

W Gong, C Pan, P Cheng, J Wang, G Zhao… - Frontiers in …, 2022 - frontiersin.org
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. As a
result of the coronavirus disease 2019 (COVID-19) pandemic, the global TB mortality rate in …

Immunogenetics of HIV disease

MP Martin, M Carrington - Immunological reviews, 2013 - Wiley Online Library
Host genetic factors are a major contributing factor to the inter‐individual variation observed
in response to human immunodeficiency virus (HIV) infection and are linked to resistance to …

HLA-B* 51 and Behçet disease

A Gul, S Ohno - Ocular immunology and inflammation, 2012 - Taylor & Francis
Behçet disease (BD) is a multisystem inflammatory disorder of unknown etiology. BD has a
multifactorial pathogenesis, and genetics plays a critical role in the development of the …

Effective suppression of HIV-1 replication by cytotoxic T lymphocytes specific for Pol epitopes in conserved mosaic vaccine immunogens

C Zou, H Murakoshi, N Kuse, T Akahoshi… - Journal of …, 2019 - Am Soc Microbiol
Cytotoxic T lymphocytes (CTLs) with strong abilities to suppress HIV-1 replication and
recognize circulating HIV-1 could be key for both HIV-1 cure and prophylaxis. We recently …

HLA class I or class II and disease association: catch the difference if you can

MT Fiorillo, F Paladini, V Tedeschi… - Frontiers in …, 2017 - frontiersin.org
The association of autoimmune diseases with HLA has been known for many decades. To
date, however, the underlying mechanisms have not been fully understood. The recently …

HLA-B may be more protective against HIV-1 than HLA-A because it resists negative regulatory factor (Nef) mediated down-regulation

US Rajapaksa, D Li, YC Peng… - Proceedings of the …, 2012 - National Acad Sciences
Human leukocyte antigen HLA-B alleles have better protective activity against HIV-1 than
HLA-A alleles, possibly due to differences in HLA-restricted HIV-1-specific CD8+ cytotoxic T …

Reduced risk of BK polyomavirus infection in HLA-B51–positive kidney transplant recipients

HF Wunderink, GW Haasnoot, CS de Brouwer… - …, 2019 - journals.lww.com
Background. Identification of specific HLA alleles and T-cell epitopes that influence the
course of BK polyomavirus (BKPyV) infection after kidney transplantation (KTx), including …

Distinct tumour antigen-specific T-cell immune response profiles at different hepatocellular carcinoma stages

C Zang, Y Zhao, L Qin, G Liu, J Sun, K Li, Y Zhao… - BMC cancer, 2021 - Springer
Abstract Background Cancer-testis antigens (CTAs) and tumour-associated antigens (TAAs)
are frequently expressed in hepatocellular carcinoma (HCC); however, the role of tumour …

Immunogenetics of HIV and HIV associated tuberculosis

S Raghavan, K Alagarasu, P Selvaraj - Tuberculosis, 2012 - Elsevier
Tuberculosis (TB) is the frequent major opportunistic infection in HIV-infected patients, and is
the leading cause of mortality among HIV-infected patients. Genetic susceptibility to TB in …

High frequency of HIV mutations associated with HLA-c suggests enhanced HLA-c–restricted CTL selective pressure associated with an AIDS-protective …

ME Blais, Y Zhang, T Rostron, H Griffin… - The Journal of …, 2012 - journals.aai.org
Delayed HIV-1 disease progression is associated with a single nucleotide polymorphism
upstream of the HLA-C gene that correlates with differential expression of the HLA-C Ag …