Seminal biomarkers for the evaluation of male infertility

JM Bieniek, AP Drabovich, KC Lo - Asian journal of andrology, 2016 - journals.lww.com
For men struggling to conceive with their partners, diagnostic tools are limited and often
consist of only a standard semen analysis. This baseline test serves as a crude estimation of …

Understanding the seminal plasma proteome and its role in male fertility

M Camargo, P Intasqui, RP Bertolla - Basic and clinical andrology, 2018 - Springer
Seminal plasma is a complex fluid comprised of secretions from the seminal vesicles, the
prostate, bulbourethral glands and from the seminiferous tubule lumen/epididymides/vasa …

What is targeted proteomics? A concise revision of targeted acquisition and targeted data analysis in mass spectrometry

E Borràs, E Sabidó - Proteomics, 2017 - Wiley Online Library
Targeted proteomics has gained significant popularity in mass spectrometry‐based protein
quantification as a method to detect proteins of interest with high sensitivity, quantitative …

Preclinical evaluation of a TEX101 protein ELISA test for the differential diagnosis of male infertility

D Korbakis, C Schiza, D Brinc, A Soosaipillai… - BMC medicine, 2017 - Springer
Background TEX101 is a cell membrane protein exclusively expressed by testicular germ
cells and shed into seminal plasma. We previously verified human TEX101 as a biomarker …

Rational design and development of SARS-CoV-2 serological diagnostics by immunoprecipitation-targeted proteomics

Z Fu, Y Rais, D Dara, D Jackson… - Analytical …, 2022 - ACS Publications
Current design of serological tests utilizes conservative immunoassay approaches and is
focused on fast and convenient assay development, throughput, straightforward …

Non-invasive diagnostics of male spermatogenesis from seminal plasma: seminal proteins

M Ješeta, A Pospíšilová, L Mekiňová, K Franzová… - Diagnostics, 2023 - mdpi.com
The compounds of seminal plasma have great potential as biomarkers of male fertility and
can be used as a diagnostic tool for types of azoospermia. Azoospermia occurs in …

Redefining serological diagnostics with immunoaffinity proteomics

J Walter, Z Eludin, AP Drabovich - Clinical Proteomics, 2023 - Springer
Serological diagnostics is generally defined as the detection of specific human
immunoglobulins developed against viral, bacterial, or parasitic diseases. Serological tests …

Comparative proteomics analysis of human FFPE testicular tissues reveals new candidate biomarkers for distinction among azoospermia types and subtypes

K Davalieva, A Rusevski, M Velkov, P Noveski… - Journal of …, 2022 - Elsevier
Understanding molecular mechanisms that underpin azoospermia and discovery of
biomarkers that could enable reliable, non-invasive diagnosis are highly needed. Using …

Harnessing male germline epigenomics for the genetic improvement in cattle

X Wang, W Li, X Feng, J Li, GE Liu, L Fang… - Journal of animal science …, 2023 - Springer
Sperm is essential for successful artificial insemination in dairy cattle, and its quality can be
influenced by both epigenetic modification and epigenetic inheritance. The bovine germline …

Emerging role of novel seminal plasma bio-markers in Male infertility: a review

N Kumar, NK Singh - European Journal of Obstetrics & Gynecology and …, 2020 - Elsevier
Male infertility has emerged as an important cause of infertility worldwide. There are many
factors affecting male fertility and research is going on to know impact of various factors on …