Current advancements in pectin: extraction, properties and multifunctional applications

V Chandel, D Biswas, S Roy, D Vaidya, A Verma… - Foods, 2022 - mdpi.com
Pectin is a heterogeneous hydrocolloid present in the primary cell wall and middle lamella in
all dicotyledonous plants, more commonly in the outer fruit coat or peel as compared to the …

The natural cytotoxicity receptors in health and disease

AD Barrow, CJ Martin, M Colonna - Frontiers in immunology, 2019 - frontiersin.org
The Natural Cytotoxicity Receptors (NCRs), NKp46, NKp44, and NKp30, were some of the
first human activating Natural Killer (NK) cell receptors involved in the non-MHC-restricted …

Spatial genomics enables multi-modal study of clonal heterogeneity in tissues

T Zhao, ZD Chiang, JW Morriss, LM LaFave… - Nature, 2022 - nature.com
The state and behaviour of a cell can be influenced by both genetic and environmental
factors. In particular, tumour progression is determined by underlying genetic aberrations …

Single-cell RNA sequencing reveals functional heterogeneity of glioma-associated brain macrophages

N Ochocka, P Segit, KA Walentynowicz… - Nature …, 2021 - nature.com
Microglia are resident myeloid cells in the central nervous system (CNS) that control
homeostasis and protect CNS from damage and infections. Microglia and peripheral …

Evolution of immune and stromal cell states and ecotypes during gastric adenocarcinoma progression

R Wang, S Song, J Qin, K Yoshimura, F Peng, Y Chu… - Cancer cell, 2023 - cell.com
Understanding tumor microenvironment (TME) reprogramming in gastric adenocarcinoma
(GAC) progression may uncover novel therapeutic targets. Here, we performed single-cell …

Targeting tumor and bone microenvironment: Novel therapeutic opportunities for castration-resistant prostate cancer patients with bone metastasis

S Li, Y Kang, Y Zeng - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2024 - Elsevier
Despite standard hormonal therapy that targets the androgen receptor (AR) attenuates
prostate cancer (PCa) effectively in the initial stage, the tumor ultimately converts to …

Reviewing the recent advances in application of pectin for technical and health promotion purposes: From laboratory to market

M Moslemi - Carbohydrate Polymers, 2021 - Elsevier
Pectin is natural biopolymer derived from various plant sources and its activity is driven by
functional groups. Affinity of pectin and chemical interactions of the active sites to chemicals …

Idiopathic pulmonary fibrosis and lung cancer: mechanisms and molecular targets

B Ballester, J Milara, J Cortijo - International journal of molecular sciences, 2019 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is the most common idiopathic interstitial pulmonary
disease with a median survival of 2–4 years after diagnosis. A significant number of IPF …

Galectin-3 as a next-generation biomarker for detecting early stage of various diseases

A Hara, M Niwa, K Noguchi, T Kanayama, A Niwa… - Biomolecules, 2020 - mdpi.com
Galectin-3 is a β-galactoside-binding lectin which is important in numerous biological
activities in various organs, including cell proliferation, apoptotic regulation, inflammation …

Platelet glycoprotein VI promotes metastasis through interaction with cancer cell–derived galectin-3

E Mammadova-Bach, J Gil-Pulido… - Blood, The Journal …, 2020 - ashpublications.org
Increasing evidence suggests that platelets play a predominant role in colon and breast
cancer metastasis, but the underlying molecular mechanisms remain elusive. Glycoprotein …