Detergent-free isolation of membrane proteins and strategies to study them in a near-native membrane environment

B Krishnarjuna, A Ramamoorthy - Biomolecules, 2022 - mdpi.com
Atomic-resolution structural studies of membrane-associated proteins and peptides in a
membrane environment are important to fully understand their biological function and the …

Structure-function analyses of new SARS-CoV-2 variants B. 1.1. 7, B. 1.351 and B. 1.1. 28.1: clinical, diagnostic, therapeutic and public health implications

J Singh, J Samal, V Kumar, J Sharma, U Agrawal… - Viruses, 2021 - mdpi.com
SARS-CoV-2 (Severe Acute Respiratory Syndrome-Coronavirus 2) has accumulated
multiple mutations during its global circulation. Recently, three SARS-CoV-2 lineages, B …

Pathology of coronavirus infections: A review of lesions in animals in the one-health perspective

V Zappulli, S Ferro, F Bonsembiante, G Brocca… - Animals, 2020 - mdpi.com
Simple Summary Coronaviruses are worldwide distributed RNA-viruses affecting several
species, causing a broad spectrum of diseases with a zoonotic potential and the ability to …

[HTML][HTML] Genetic characteristics and phylogeny of 969-bp S gene sequence of SARS-CoV-2 from Hawai 'i reveals the worldwide emerging P681H mutation

DP Maison, LL Ching, CM Shikuma… - Hawai'i journal of …, 2021 - ncbi.nlm.nih.gov
The COVID-19 pandemic has ravaged the world, caused over 1.8 million deaths in its first
year, and severely affected the global economy. Hawai 'i has not been spared from the …

[HTML][HTML] Azadirachta indica A. Juss bark extract and its Nimbin isomers restrict β-coronaviral infection and replication

L Sarkar, L Oko, S Gupta, AN Bubak, B Das, P Gupta… - Virology, 2022 - Elsevier
Emerging mutations in the SARS-CoV-2 genome pose a challenge for vaccine development
and antiviral therapy. The antiviral efficacy of Azadirachta indica bark extract (NBE) was …

Homologous recombination shapes the genetic diversity of African swine fever viruses

Z Zhu, CT Xiao, Y Fan, Z Cai, C Lu, G Zhang… - Veterinary …, 2019 - Elsevier
The African swine fever virus (ASFV) has severely influenced the swine industry of the world.
Currently, there is no effective vaccine or drugs against the ASFV. How to effectively control …

CD40L protects against mouse hepatitis virus-induced neuroinflammatory demyelination

F Saadi, D Chakravarty, S Kumar, M Kamble… - PLoS …, 2021 - journals.plos.org
Neurotropic mouse hepatitis virus (MHV-A59/RSA59) infection in mice induces acute
neuroinflammation due to direct neural cell dystrophy, which proceeds with demyelination …

Azadirachta indica A. Juss Ameliorates Mouse Hepatitis Virus-Induced Neuroinflammatory Demyelination by Modulating Cell-to-Cell Fusion in an Experimental …

L Sarkar, RK Putchala, AA Safiriyu… - Frontiers in Cellular …, 2020 - frontiersin.org
Mouse hepatitis virus (MHV)-induced murine neuroinflammation serves as a model to study
acute meningoencephalomyelitis, hepatitis, and chronic neuroinflammatory demyelination; …

Ifit2 deficiency restricts microglial activation and leukocyte migration following murine coronavirus (m-CoV) CNS infection

J Das Sarma, A Burrows, P Rayman, MH Hwang… - PLoS …, 2020 - journals.plos.org
The interferon-induced tetratricopeptide repeat protein (Ifit2) protects mice from lethal
neurotropic viruses. Neurotropic coronavirus MHV-RSA59 infection of Ifit2-/-mice caused …

[HTML][HTML] Matrix metalloproteinases and tissue inhibitors of metalloproteinases in murine β-coronavirus-induced neuroinflammation

S Sengupta, S Addya, D Biswas, P Banerjee, JD Sarma - Virology, 2022 - Elsevier
Mouse hepatitis virus (MHV; m-β-CoV) serves as a useful model for studying the cellular
factors involved in neuroinflammation. To understand the role of matrix metalloproteinases …