Atrial fibrillation is the most common arrhythmia worldwide with increasing frequency noted
with age. Hyperthyroidism is a well-known cause of atrial fibrillation with a 16%–60 …

G protein–coupled receptors (GPCRs) are the largest superfamily of receptors encoded by
the human genome, and represent the largest class of current drug targets. Over the last …

Infection-triggered disease onset, chronic immune activation and autonomic dysregulation in
CFS point to an autoimmune disease directed against neurotransmitter receptors …

The electrocardiographic PR interval reflects atrioventricular conduction, and is associated
with conduction abnormalities, pacemaker implantation, atrial fibrillation (AF), and …

Immune checkpoint inhibitors (ICIs) have transformed the treatment of various cancers,
including malignancies once considered untreatable. These agents, however, are …

Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy. However, their use
is frequently associated with immune‐related adverse events (irAEs) potentially affecting …

Background Both the adrenergic and renin‐angiotensin systems contribute to orthostatic
circulatory homeostasis, which is impaired in postural orthostatic tachycardia syndrome …

The broad application of immune checkpoint inhibitors (ICIs) has led to significant gains in
cancer outcomes. By abrogating inhibitory signals, ICIs promote T cell targeting of cancer …

Growing evidence indicates a cardio-pathogenic role of autoantibodies against β 1-
adrenergic receptors (β 1 AR). In particular autoantibodies stimulating β 1 AR-mediated …

Atrial fibrillation (AF) is the most common type of cardiac arrhythmia. To date, a lot of
research has been conducted to investigate the underlying mechanisms of this disease at …