Infection of the colon with the Gram-positive bacterium Clostridium difficile is potentially life
threatening, especially in elderly people and in patients who have dysbiosis of the gut …

Clostridium difficile infection (CDI) continues to affect patients in hospitals and communities
worldwide. The spectrum of clinical disease ranges from mild diarrhoea to toxic megacolon …

Abstract Background Efforts to prevent Clostridioides difficile infection continue to expand
across the health care spectrum in the United States. Whether these efforts are reducing the …

Background Clostridium difficile is the most common cause of infectious diarrhea in
hospitalized patients. Recurrences are common after antibiotic therapy. Actoxumab and …

Clostridium difficile disease has recently increased to become a dominant nosocomial
pathogen in North America and Europe, although little is known about what has driven this …

Clostridium difficile infection (CDI) has significant clinical impact especially on the elderly
and/or immunocompromised patients. The pathogenicity of Clostridium difficile is mainly …

Clostridium difficile infection (CDI) is the leading cause of antimicrobial and health care-
associated diarrhea in humans, presenting a significant burden to global health care …

Clostridium difficile is a leading cause of antibiotic-associated diarrhea, a significant animal
pathogen, and a worldwide public health burden. Most disease-causing strains secrete two …

Antimicrobial resistance (AMR) in Clostridioides difficile remains a significant threat to global
healthcare systems, not just for the treatment of C. difficile infection (CDI), but as a reservoir …

Clostridioides difficile remains an important public health threat, globally. Since the
emergence of the hypervirulent strain, ribotype 027, new strains have been reported to …