Tabular data—rows of samples and columns of sample features—are ubiquitously used
across disciplines. Yet the tabular representation makes it difficult to discover underlying …

Visceral leishmaniasis is a potentially devastating neglected tropical disease caused by the
protozoan parasites Leishmania donovani and L. infantum (chagasi). These parasites reside …

Human papillomavirus (HPV)‐associated cancer continues to evade the immune system by
promoting a suppressive tumor microenvironment. Therefore, immunotherapy appears to be …

Objective Most patients with pancreatic ductal adenocarcinoma (PDAC) will experience
recurrence after resection. Here, we investigate spatially organised immune determinants of …

Background Individual T cell responses vary significantly based on the microenvironment
present at the time of immune response and on prior induced T cell memory. While the cecal …

The coexistence of ulcerative colitis (UC) and nonalcoholic steatohepatitis (NASH) involves
a intricate interplay, though the precise pathophysiological mechanisms remain elusive. To …

In this study, we investigated the molecular differences between patients with typical
obstetric antiphospholipid syndrome (OAPS) and patients with non-criteria obstetric …

Abstract Background Immune checkpoint inhibitors (ICIs) are widely used in cancer
treatment; however, the emergence of ICI-associated myocarditis (ICI-MC) presents a severe …

An external validation cohort of 109 PDACs was examined in parallel. These included 33
PDACs with liver recurrences (30.3%; liver and any other sites), 20 cases with lung …

Metastatic castration-resistant prostate cancer (mCRPC) is a heterogeneous disease
characterised by the lack of durable responses to standard therapies currently approved for …