Privileged structures have been widely used as an effective template for the research and
discovery of high value chemicals. Coumarin is a simple scaffold widespread in Nature and …

Pyrazole and its derivatives are considered a pharmacologically important active scaffold
that possesses almost all types of pharmacological activities. The presence of this nucleus in …

Heading the list of the critical health-related issues worldwide, cancer continues to be a one
of the most serious life-threatening diseases. The rate of cancer-related mortality is at …

The pyrazole nucleus is an aromatic azole heterocycle with two adjacent nitrogen atoms.
Pyrazole derivatives have exhibited a broad spectrum of biological activities, and approved …

Many researchers around the world are working on the development of novel anticancer
drugs with different mechanisms of action. In this case, coumarin is a highly promising …

Tuberculosis (TB) is a lift-threatening chronic deadliest infectious disease caused
predominantly by Mycobacterium tuberculosis (MTB) which affects primarily the lungs …

Coumarins are natural products characterized as 1, 2 benzopyrones widely distributed in
plants, as well as, in many species of fungi and bacteria. Nowadays, many synthetic …

The study of coumarin dates back to 1820 when coumarin was first extracted from tonka
bean by Vogel. Compounds containing coumarin backbone are a very important group of …

Simple Summary Coumarins are a large family of benzopyrones, and more than 1300
coumarins have been reported to date. Natural, as well as synthetic, coumarins have …

Diabetes is a group of metabolic diseases characterised by chronic hyperglycaemia caused
by multiple causes, which is caused by insulin secretion and/or utilisation defects. It is …