The dentate gyrus (DG) has a key role in hippocampal memory formation. Intriguingly, DG
lesions impair many, but not all, hippocampus-dependent mnemonic functions, indicating …

The human ventromedial prefrontal cortex (vmPFC)/anterior cingulate cortex is implicated in
reward and emotion, but also in memory. It is shown how the human orbitofrontal cortex …

The dentate gyrus (DG) gates neocortical information flow to the hippocampus. Intriguingly,
the DG also produces adult-born dentate granule cells (abDGCs) throughout the lifespan …

The dentate gyrus of the mammalian hippocampus continuously generates new neurons
during adulthood. These adult-born neurons become functionally active and are thought to …

Applications that generate huge amounts of data in the form of fast streams are becoming
increasingly prevalent, being therefore necessary to learn in an online manner. These …

Sharp wave ripples (SPW‐Rs) represent the most synchronous population pattern in the
mammalian brain. Their excitatory output affects a wide area of the cortex and several …

We update complementary learning systems (CLS) theory, which holds that intelligent
agents must possess two learning systems, instantiated in mammalians in neocortex and …

The hippocampus is critical for learning and memory, relying in part on pattern separation
processes supported by the dentate gyrus (DG) to prevent interference from overlapping …

The incorporation of new information into the hippocampal network is likely to be
constrained by its innate architecture and internally generated activity patterns. However, the …

Many attempts have been made to localize the physical trace of a memory, or engram, in the
brain. However, until recently, engrams have remained largely elusive. In this Review, we …