Pathogenic fungi have emerged as significant causes of infectious morbidity and death in
patients with acquired immunodeficiency conditions such as HIV/AIDS and following receipt …

Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …

Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …

Invasive candidiasis is an important health-care-associated fungal infection that can be
caused by several Candida spp.; the most common species is Candida albicans, but the …

Candida species, belonging to commensal microbial communities in humans, cause
opportunistic infections in individuals with impaired immunity. Pathogens encountered in …

Despite advances in antifungal therapy, the mortality associated with invasive candidiasis
remains as high as 40%. This review summarizes recent trends and current strategies …

The immune response to Candida species is shaped by the commensal character of the
fungus. There is a crucial role for discerning between colonization and invasion at mucosal …

As part of the Human Functional Genomics Project, which aims to understand the factors that
determine the variability of immune responses, we investigated genetic variants affecting …

Invasive candidiasis is the most common critical care-associated fungal infection with a
crude mortality of~ 40–55%. Important factors contributing to risk of invasive candidiasis in …

Systemic candidiasis is a common, high-mortality, nosocomial fungal infection.
Unexpectedly, it has emerged as a complication of anti-complement C5-targeted …