Significance: Social and demographic changes have led to an increased prevalence of
loneliness and social isolation in modern society. Recent Advances: Population-based …

Loneliness and social isolation are common sources of chronic stress in modern society.
Epidemiological studies have demonstrated that loneliness and social isolation increase …

Exposure of an organism to chronic psychosocial stress may affect brain-derived
neurotrophic factor (BDNF) expression that has been implicated in the etiology of psychiatric …

Various stressors may disrupt the redox homeostasis of an organism by causing oxidative
and nitrosative stress that may activate stressor-specific pathways and provoke specific …

Physical or psychological stress can cause an immunologic imbalance that disturbs the
central nervous system followed by neuroinflammation. The association between …

Major depressive disorder (MDD) is estimated to impose maximum debilitating effects on the
society by 2030, with its critical effects on health, functioning, quality of life and concomitant …

The effects of C60FAS (50 and 500 μg/kg) supplementation, in a normal physiological state
and after restraint stress exposure, on prooxidant/antioxidant balance in rat tissues were …

Without healing, multicellular life on Earth would not exist. Without healing, one injury
predisposes to another, leading to disability, chronic disease, accelerated aging, and death …

Major depressive disorder (MDD) is a multifactorial neuropsychiatric disorder. Chronic
administration of corticosterone (CORT) to rodents is used to mimic the stress associated …

Agmatine, an endogenous neuromodulator, is a potential candidate to constitute an
adjuvant/monotherapy for the management of depression. A recent study by our group …