Neuroinflammation and oxidative stress in the pathogenesis of autism spectrum disorder

N Usui, H Kobayashi, S Shimada - International Journal of Molecular …, 2023 - mdpi.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder (NDD) characterized by
impairments in social communication, repetitive behaviors, restricted interests, and …

Natural antioxidants: a novel therapeutic approach to autism spectrum disorders?

L Pangrazzi, L Balasco, Y Bozzi - Antioxidants, 2020 - mdpi.com
Autism spectrum disorders (ASD) are a group of neurodevelopmental syndromes with both
genetic and environmental origins. Several recent studies have shown that inflammation …

Cannabidivarin treatment ameliorates autism-like behaviors and restores hippocampal endocannabinoid system and glia alterations induced by prenatal valproic acid …

E Zamberletti, M Gabaglio… - Frontiers in cellular …, 2019 - frontiersin.org
Autism spectrum disorder (ASD) is a developmental condition whose primary features
include social communication and interaction impairments with restricted or repetitive motor …

The role of sensorimotor difficulties in autism spectrum conditions

P Hannant, T Tavassoli, S Cassidy - Frontiers in neurology, 2016 - frontiersin.org
In addition to difficulties in social communication, current diagnostic criteria for autism
spectrum conditions (ASC) also incorporate sensorimotor difficulties, repetitive motor …

Astaxanthin improves behavioral disorder and oxidative stress in prenatal valproic acid-induced mice model of autism

MM Al-Amin, MM Rahman, FR Khan, F Zaman… - Behavioural brain …, 2015 - Elsevier
Prenatal exposure to valproic acid on gestational day 12.5 may lead to the impaired
behavior in the offspring, which is similar to the human autistic symptoms. To the contrary …

A randomized double blind placebo controlled clinical trial of N-Acetylcysteine added to risperidone for treating autistic disorders

A Ghanizadeh, E Moghimi-Sarani - BMC psychiatry, 2013 - Springer
Background This study examined the efficacy and safety of N-acetylcysteine (NAC)
augmentation for treating irritability in children and adolescents with autism spectrum …

Chronic inflammatory diseases and green tea polyphenols

HS Oz - Nutrients, 2017 - mdpi.com
Chronic inflammatory diseases affect millions of people globally and the incidence rate is on
the rise. While inflammation contributes to the tissue healing process, chronic inflammation …

Polyphenol compounds and PKC signaling

J Das, R Ramani, MO Suraju - … et Biophysica Acta (BBA)-General Subjects, 2016 - Elsevier
Background Naturally occurring polyphenols found in food sources provide huge health
benefits. Several polyphenolic compounds are implicated in the prevention of disease …

Fragile X syndrome: from molecular pathology to therapy

T Maurin, S Zongaro, B Bardoni - Neuroscience & Biobehavioral Reviews, 2014 - Elsevier
Abstract Fragile X Syndrome (FXS) is the most common form of inherited intellectual
disability due to the silencing of the FMR1 gene encoding FMRP (Fragile X Mental …

N-acetylcysteine as an adjunctive therapy to risperidone for treatment of irritability in autism: a randomized, double-blind, placebo-controlled clinical trial of efficacy …

M Nikoo, H Radnia, M Farokhnia… - Clinical …, 2015 - journals.lww.com
Objectives According to the proposed interference of N-acetylcysteine (NAC) with
pathophysiologic processes of autistic disorders (ADs), we aimed to assess the …