Consensus on molecular imaging and theranostics in neuroendocrine neoplasms

V Ambrosini, J Kunikowska, E Baudin, L Bodei… - European journal of …, 2021 - Elsevier
Nuclear medicine plays an increasingly important role in the management neuroendocrine
neoplasms (NEN). Somatostatin analogue (SSA)-based positron emission …

EANM dosimetry committee recommendations for dosimetry of 177Lu-labelled somatostatin-receptor-and PSMA-targeting ligands

K Sjögreen Gleisner, N Chouin, PM Gabina… - European journal of …, 2022 - Springer
The purpose of the EANM Dosimetry Committee is to provide recommendations and
guidance to scientists and clinicians on patient-specific dosimetry. Radiopharmaceuticals …

ICRU REPORT 96, dosimetry-guided radiopharmaceutical therapy

G Sgouros, WE Bolch, A Chiti… - Journal of the …, 2021 - journals.sagepub.com
The International Commission on Radiation Units and Measurements (ICRU), since its
inception in 1925, has had as its principal objective the development of internationally …

Phase II trial demonstrates the efficacy and safety of individualized, dosimetry-based 177Lu-DOTATATE treatment of NET patients

A Sundlöv, KS Gleisner, J Tennvall… - European journal of …, 2022 - Springer
Abstract Purpose Radionuclide therapy with 177Lu-DOTATATE is well established for
patients with advanced somatostatin receptor–positive neuroendocrine tumors with a …

Quantitative SPECT/CT for dosimetry of peptide receptor radionuclide therapy

J Kennedy, A Chicheportiche, Z Keidar - Seminars in nuclear medicine, 2022 - Elsevier
Neuroendocrine tumors (NETs) are uncommon malignancies of increasing incidence and
prevalence. As these slow growing tumors usually overexpress somatostatin receptors …

Optimization of the radiation dosimetry protocol in Lutetium-177-PSMA therapy: toward clinical implementation

SMB Peters, MCT Mink, BM Privé, M de Bakker… - EJNMMI research, 2023 - Springer
Abstract Background Dosimetry in [177Lu] Lu-PSMA therapy is a valuable tool to assess
treatment efficacy and toxicity. This study aims to develop a clinically implementable protocol …

Dosimetric quantities in neuroendocrine tumors over treatment cycles with 177Lu-DOTATATE

D Roth, J Gustafsson, CF Warfvinge… - Journal of Nuclear …, 2022 - Soc Nuclear Med
Tumor dosimetry was performed for 177Lu-DOTATATE with the aims of better understanding
the range and variation of the tumor-absorbed doses (ADs), how different dosimetric …

A novel time–activity information-sharing approach using nonlinear mixed models for patient-specific dosimetry with reduced imaging time points: Application in …

TP Devasia, YK Dewaraja, KA Frey… - Journal of Nuclear …, 2021 - Soc Nuclear Med
Multiple-time-point SPECT/CT imaging for dosimetry is burdensome for patients and lacks
statistical efficiency. A novel method for joint kidney time–activity estimation based on a …

Relationships between uptake of [68Ga]Ga-DOTA-TATE and absorbed dose in [177Lu]Lu-DOTA-TATE therapy

A Stenvall, J Gustafsson, E Larsson, D Roth… - EJNMMI research, 2022 - Springer
Abstract Background Somatostatin receptor 68Ga PET imaging is standard for evaluation of
a patient's suitability for 177Lu peptide receptor radionuclide therapy of neuroendocrine …

Feasibility and accuracy of single time point imaging for renal dosimetry following 177Lu-DOTATATE ('Lutate') therapy

KP Willowson, E Eslick, H Ryu, A Poon, EJ Bernard… - EJNMMI physics, 2018 - Springer
Background This study aims to assess both feasibility and accuracy of renal dosimetry
imaging protocols in patients receiving Lutate therapy for neuroendocrine tumours (NETs) …