Collective cell migration is a key driver of embryonic development, wound healing, and
some types of cancer invasion. Here, we provide a physical perspective of the mechanisms …

Collective cell migration plays a central role in tissue development, morphogenesis, wound
repair and cancer progression. With the growing realization that physical forces mediate cell …

Abstract Development, regeneration and cancer involve drastic transitions in tissue
morphology. In analogy with the behaviour of inert fluids, some of these transitions have …

Collective epithelial behaviors are essential for the development of lumens in organs.
However, conventional assays of planar systems fail to replicate cell cohorts of tubular …

During the growth of a cell collective, such as proliferating microbial colonies and epithelial
tissues, the local cell growth increases the local pressure, which in turn suppresses cell …

Collective cell migration contributes to embryogenesis, wound healing and tumour
metastasis. Cell monolayer migration experiments help in understanding what determines …

Tissues do not exist in isolation—they interact with other tissues within and across organs.
While cell-cell interactions have been intensely investigated, less is known about tissue …

During the spreading of epithelial tissues, the advancing tissue front often develops
fingerlike protrusions. Their resemblance to traditional viscous fingering patterns in driven …

Collective cell migration in spreading epithelia in controlled environments has become a
landmark in our current understanding of fundamental biophysical processes in …

We present a hydrodynamic theory to describe shear flows in developing epithelial tissues.
We introduce hydrodynamic fields corresponding to state properties of constituent cells as …