Human tissue kallikreins (hKs), which are encoded by the largest contiguous cluster of
protease genes in the human genome, are secreted serine proteases with diverse …

The 15 members of the kallikrein-related serine peptidase (KLK) family have diverse tissue-
specific expression profiles and putative proteolytic functions. The kallikrein family is also …

Purpose MicroRNAs (miRNAs) play an essential role in breast malignant tumor
development and progression. The development of clinically validated biomarkers for …

Purpose: CD24 is expressed in hematological malignancies as well as in a large variety of
solid tumors including breast cancer. We aimed to evaluate CD24 protein expression in …

Tissue kallikreins are members of the S1 family (clan SA) of trypsin-like serine proteases
and are present in at least six mammalian orders. In humans, tissue kallikreins (hK) are …

Kallikreins are a subgroup of the serine protease enzyme family. Until recently, it was
thought that the human kallikrein gene family contained only three members. In the past 3 …

Prostate specific antigen (PSA) or human kallikrein 3 (hK3) has long been an effective
biomarker for prostate cancer. Now, other members of the tissue kallikrein (KLK) gene family …

Human tissue kallikreins (KLKs) are attracting increased attention due to their role as
biomarkers for the screening, diagnosis, prognosis, and monitoring of various cancers …

A" bottom-up" proteomics approach and a two-dimensional (strong cation exchange
followed by reversed-phase) LC-MS/MS strategy on a linear ion trap (LTQ) were utilized to …

Human tissue kallikrein genes, located on the long arm of chromosome 19, are a subgroup
of the serine protease family of proteolytic enzymes. Initially thought to consist of three …