Hypertension is a global health problem, with> 1.3 billion individuals with high blood
pressure worldwide. In this Review, we present an inflammatory paradigm for hypertension …

The lymphatic system (LS) is composed of lymphoid organs and a network of vessels that
transport interstitial fluid, antigens, lipids, cholesterol, immune cells, and other materials in …

The cardiac lymphatic network plays a key role in regulation of myocardial extracellular
volume and immune cell homeostasis. In different pathological conditions cardiac …

The mammalian vascular system consists of two networks: the blood vascular system and
the lymphatic vascular system. Throughout the body, the lymphatic system contributes to …

Aim In recent decades, there has been a revolutionary decrease in cancer-related mortality
and an increase in survival due to the introduction of novel targeted drugs. Nevertheless …

The lymphatic vasculature is involved in the pathogenesis of acute cardiac injuries, but little
is known about its role in chronic cardiac dysfunction. Here, we demonstrate that …

Aims Excess dietary sodium intake and retention lead to hypertension. Impaired dermal
lymphangiogenesis and lymphatic dysfunction–mediated sodium and fluid imbalance are …

Aims Lymphatics are essential for cardiac health, and insufficient lymphatic expansion
(lymphangiogenesis) contributes to development of heart failure (HF) after myocardial …

Angiogenesis and immunosuppression are closely related pathophysiologic processes.
Widely prescribed in malignant tumor and proliferative retinal lesions, VEGF signaling …

Cardiac lymphangiogenesis plays an important physiological role in the regulation of
interstitial fluid homeostasis, inflammatory, and immune responses. Impaired or excessive …