Triple-Dearomative Photocycloaddition: A Strategy to Construct Caged Molecular Frameworks

K Ji, J Parthiban, S Jockusch, J Sivaguru… - Journal of the …, 2024 - ACS Publications
An unprecedented caged 2H-benzo-dioxo-pentacycloundecane framework was
serendipitously obtained in a single transformation via triple-dearomative …

Versatile Biological Activities of Thiosemicarbazones and Their Metal Complexes

SB Zahra, A Khan, N Ahmed, M Rafique… - Journal of Molecular …, 2024 - Elsevier
One of the most crucial objectives in medicinal chemistry is the development of innovative
and beneficial bioactive compounds with various biological activities. Thiosemicarbazone …

Unlocking therapeutic potential: the role of adamantane in drug discovery

C Dane, GA Cumbers, B Allen… - Australian Journal of …, 2024 - CSIRO Publishing
The unique structural and physicochemical properties of adamantane and its derivatives
have attracted considerable attention in the field of medicinal chemistry. Substituting phenyl …

Engineering aptamers to enhance their interaction with protein target for selective inhibition of cell surface receptors

L Song, Y Wang, Y Guo, S Bulale, M Zhou, F Yu… - International Journal of …, 2024 - Elsevier
Cell surface receptors play a key role in intracellular signaling, and their overexpression and
activation are among the drivers of multiple diseases. Selective inhibition of cell surface …

Asymmetric aza-Henry reaction toward trifluoromethyl β-nitroamines and biological investigation of their adamantane-type derivatives

Y Ren, M Du, Z Peng, C Zheng, G Zhao - Frontiers in Chemistry, 2024 - frontiersin.org
Amino acid-derived quaternary ammonium salts were successfully applied in the
asymmetric aza-Henry reaction of nitromethane to N-Boc trifluoromethyl ketimines. α …

Chiral spherical aromatic amides: one-step synthesis and their stereochemical/chiroptical properties

D Koike, H Masu, S Kikkawa, A Chiba… - Organic & …, 2024 - pubs.rsc.org
Macrocyclic aromatic amides 2, in which the meta-positions of all four benzene rings are
linked by tertiary amide bonds, were successfully synthesized by a one-step condensation …

Triple-Dearomative Photocycloaddition–A Strategy to Construct Novel Caged Molecular Frameworks

J Parthiban, S Jockusch, J Sivaguru - 2024 - chemrxiv.org
An unprecedented, caged 2H-benzo-dioxo-pentacycloundecane (BDPC) framework was
serendipitously obtained in a single transformation via a triple-dearomative …

Triple-Dearomative Photocycloaddition–A Strategy to Construct Novel Caged Molecular Frameworks

K Ji, J Parthiban, S Jockusch, J Sivaguru, J Porco Jr - 2024 - chemrxiv.org
An unprecedented, caged 2H-benzo-dioxo-pentacycloundecane (BDPC) framework was
serendipitously obtained in a single transformation via a triple-dearomative …

[HTML][HTML] Экспериментальная фармакокинетика нового противопаркинсонического средства АДК-1113

ОЮ Кравцова, ДА Дворянинов… - Фармакокинетика и …, 2024 - cyberleninka.ru
Изучена фармакокинетика нового противопаркинсонического средства АДК-1113 после
однократных внутривенного и внутрижелудочного введений мышам в дозах 10 и 20 …