PEGylation for enhancing nanoparticle diffusion in mucus

JT Huckaby, SK Lai - Advanced drug delivery reviews, 2018 - Elsevier
The viscoelastic mucus secretions coating exposed organs such as the lung airways and the
female reproductive tract can trap and quickly eliminate not only foreign pathogens and …

Chitosan-based nanoparticles as drug delivery systems: a review on two decades of research

S Naskar, K Kuotsu, S Sharma - Journal of drug targeting, 2019 - Taylor & Francis
Chitosan (CS) is one of the most functional natural biopolymer widely used in the
pharmaceutical field due to its biocompatibility and biodegradability. These privileges lead …

The kidney-related effects of polystyrene microplastics on human kidney proximal tubular epithelial cells HK-2 and male C57BL/6 mice

YL Wang, YH Lee, YH Hsu, IJ Chiu… - Environmental …, 2021 - ehp.niehs.nih.gov
Background: Understanding the epidemic of chronic kidney disease of uncertain etiology
may be critical for health policies and public health responses. Recent studies have shown …

Oral delivery of anticancer drugs: challenges and opportunities

K Thanki, RP Gangwal, AT Sangamwar… - Journal of controlled …, 2013 - Elsevier
The present report focuses on the various aspects of oral delivery of anticancer drugs. The
significance of oral delivery in cancer therapeutics has been highlighted which principally …

The potential of chitosan in nanomedicine: An overview of the cytotoxicity of chitosan based nanoparticles

J Frigaard, JL Jensen, HK Galtung… - Frontiers in …, 2022 - frontiersin.org
The unique properties and applications of nanotechnology in targeting drug delivery,
cosmetics, fabrics, water treatment and food packaging have received increased focus the …

Nanoparticle toxicity by the gastrointestinal route: evidence and knowledge gaps

IL Bergin, FA Witzmann - International journal of biomedical …, 2013 - inderscienceonline.com
The increasing interest in nanoparticles for advanced technologies, consumer products, and
biomedical applications has led to great excitement about potential benefits but also …

Cytotoxicity, oxidative stress, apoptosis and the autophagic effects of silver nanoparticles in mouse embryonic fibroblasts

YH Lee, FY Cheng, HW Chiu, JC Tsai, CY Fang… - Biomaterials, 2014 - Elsevier
With the advancement of nanotechnology, nanomaterials have been comprehensively
applied in our modern society. However, the hazardous impacts of nanoscale particles on …

Chitosan-based advanced materials for docetaxel and paclitaxel delivery: Recent advances and future directions in cancer theranostics

M Ashrafizadeh, Z Ahmadi, N Mohamadi… - International journal of …, 2020 - Elsevier
Paclitaxel (PTX) and docetaxel (DTX) are key members of taxanes with high anti-tumor
activity against various cancer cells. These chemotherapeutic agents suffer from a number of …

Cationic polystyrene nanospheres induce autophagic cell death through the induction of endoplasmic reticulum stress

HW Chiu, T Xia, YH Lee, CW Chen, JC Tsai, YJ Wang - Nanoscale, 2015 - pubs.rsc.org
Nanoparticles (NPs) have been used to produce a wide range of products that have
applications in imaging and drug delivery in medicine. Due to their chemical stability, well …

Bioadhesive chitosan nanoparticles: dual targeting and pharmacokinetic aspects for advanced lung cancer treatment

MK Viswanadh, AK Mehata, V Sharma, V Priya… - Carbohydrate …, 2021 - Elsevier
The chitosan-folate conjugate was synthesized initially and confirmed by FTIR and NMR
spectroscopic studies. Following, docetaxel (DXL) loaded non-targeted, single receptor and …