Hereunder, we highlight bacterial membrane anionic lipids as attractive targets in the design
of antibacterial drugs which can be effective against both Gram-positive and Gram-negative …

In the recent past, prevalence of life threatening fungal diseases have increased rapidly in
immune-compromised cases such as acquired immunodeficiency syndrome (AIDS), cancer …

The extensive use of fluconazole (FLC) and other azole drugs has caused the emergence
and rise of azole-resistant fungi. The fungistatic nature of FLC in combination with toxicity …

Azoles are antifungal drugs used to treat fungal infections such as candidiasis in humans.
Their extensive use has led to the emergence of drug resistance, complicating antifungal …

Infectious diseases remain significant health concerns worldwide, and resistance is
particularly common in patients with tuberculosis caused by Mycobacterium tuberculosis …

A systematic analysis of all synthetic and chemoenzymatic methodologies for the
preparation of aminoglycosides for a variety of applications (therapeutic and agricultural) …

Epidemic diseases of crops caused by fungi deeply affected the course of human history
and processed a major restriction on social and economic development. However, with the …

Despite their inherent toxicity and the acquired bacterial resistance that continuously
threaten their long-term clinical use, aminoglycosides (AGs) still remain valuable …

Fungal infections directly affect millions of people each year. In addition to the invasive
fungal infections of humans, the plants and animals that comprise our primary food source …

Cationic amphiphiles derived from aminoglycosides (AGs) have been shown to exhibit
enhanced antimicrobial activity. Through the attachment of hydrophobic residues such as …