Inflammasomes are multiprotein complexes, which are assembled in response to a diverse
range of exogenous pathogens and endogenous danger signals, leading to produce pro …

Proliferation, metabolism, and migration of hematopoietic stem/progenitor cells (HSPCs) are
coordinated by receptors expressed on outer cell membranes that are integrated into …

Broflanilide is widely used to control pests and has attracted attention due to its adverse
effects on aquatic organisms. Our previous study showed that broflanilide has a negative …

Chronic inflammatory diseases are associated with hematopoietic lineage bias, including
neutrophilia and anemia. We have recently identified that the canonical inflammasome …

In this study, we investigated the inhibitory effect of 5-aminolevulinic acid (ALA), a heme
precursor, on inflammatory and oxidative stress activated by lipopolysaccharide (LPS) in …

Dandelions (Taraxacum spp.) play an important role in the treatment of inflammatory
diseases. In this study, we investigated the anti-inflammatory effects of Dandelion Extract …

Chronic diseases and hematopoietic disorders are associated with dysregulation of the
inflammasome. Our group has recently reported the relevance of the inflammasome in the …

Leukemic cells (LCs) arise from the hematopoietic stem/and progenitor cells (HSCs/HSPCs)
and utilize cues from the bone marrow microenvironment (BMM) for their regulation in the …

Aims: Erythropoiesis is controlled by several factors, including oxygen level under different
circumstances. However, the role of hypoxia in erythroid differentiation and the underlying …

Inflammation caused by the excessive production of pro-inflammatory mediators and
cytokines in abnormally activated macrophages promotes the initiation and progression of …