Demystifying racemic natural products in the homochiral world

GTM Bitchagno, VA Nchiozem-Ngnitedem… - Nature Reviews …, 2022 - nature.com
Natural products possess structural complexity, diversity and chirality with attractive
functions and biological activities that have significantly impacted drug discovery initiatives …

Plant-derived bioactives and oxidative stress-related disorders: a key trend towards healthy aging and longevity promotion

B Salehi, E Azzini, P Zucca, E Maria Varoni… - Applied Sciences, 2020 - mdpi.com
Plants and their corresponding botanical preparations have been used for centuries due to
their remarkable potential in both the treatment and prevention of oxidative stress-related …

Xanthones and cancer: from natural sources to mechanisms of action

LC Klein‐Júnior, A Campos, R Niero… - Chemistry & …, 2020 - Wiley Online Library
Xanthones are a class of heterocyclic natural products that have been widely studied for
their pharmacological potential. In fact, they have been serving as scaffolds for the design of …

Recent progress of antibacterial natural products: Future antibiotics candidates

J Dai, R Han, Y Xu, N Li, J Wang, W Dan - Bioorganic chemistry, 2020 - Elsevier
The discovery of novel antibacterial molecules plays a key role in solving the current
antibiotic crisis issue. Natural products have long been an important source of drug …

The role of traditional Chinese medicine in the regulation of oxidative stress in treating coronary heart disease

X Yang, T He, S Han, X Zhang, Y Sun… - Oxidative Medicine …, 2019 - Wiley Online Library
Oxidative stress has been closely related with coronary artery disease. In coronary heart
disease (CHD), an excess of reactive oxygen species (ROS) production generates …

Natural enantiomers: occurrence, biogenesis and biological properties

JH Yu, ZP Yu, RJ Capon, H Zhang - Molecules, 2022 - mdpi.com
The knowledge that natural products (NPs) are potent and selective modulators of important
biomacromolecules (eg, DNA and proteins) has inspired some of the world's most …

Antibacterial activities of plant-derived xanthones

X Liu, J Shen, K Zhu - RSC Medicinal Chemistry, 2022 - pubs.rsc.org
The increasing threat to global health posed by antibiotic resistance remains a serious
concern. This troublesome scenario has steered a need for the discovery and evaluation of …

Comparative study of 1, 1‐Diphenyl‐2‐picryl‐hydrazyl radical (DPPH•) scavenging capacity of the antioxidant xanthones family

X Li - ChemistrySelect, 2018 - Wiley Online Library
This study compares the antioxidant capacities of the xanthone family and analyzes
structure‐activity relationship. Thirty xanthones with various structural features were selected …

The genus Cratoxylum: traditional use, phytochemistry and pharmacology

NT Huong, NQ Hop, NT Son - Journal of Pharmacy and …, 2023 - academic.oup.com
Abstract Objectives The genus Cratoxylum contained medicinal herbs, which are widely
distributed in South-East Asia and China. Plants of this genus were consumed as a …

A New Phenolic Alkaloid from Halocnemum strobilaceum Endophytes: Antimicrobial, Antioxidant and Biofilm Inhibitory Activities

MMM Abdel Razek, AY Moussa… - Chemistry & …, 2020 - Wiley Online Library
Human infections caused by microbial biofilm formation represent a growing major health
threat. A new alkaloid, 3‐amino‐5‐(3‐hydroxybutan‐2‐yl)‐4‐methylphenol, was isolated …