The anterior cingulate cortex (ACC) is activated in both acute and chronic pain. In this
Review, we discuss increasing evidence from rodent studies that ACC activation contributes …

Recent neuroimaging studies suggest that the brain adapts with pain, as well as imparts risk
for developing chronic pain. Within this context, we revisit the concepts for nociception, acute …

Empathic pain has attracted the interest of a substantial number of researchers studying the
social transfer of pain in the sociological, psychological, and neuroscience fields. However …

Oxytocin is a well-known neurohypophysial hormone that plays an important role in
behavioral anxiety and nociception. Two major forms of long-term potentiation, presynaptic …

After nerve injury maladaptive changes can occur in injured sensory neurons and along the
entire nociceptive pathway within the CNS, which may lead to spontaneous pain or pain …

Neuropathic and inflammatory pain promote a large number of persisting adaptations at the
cellular and molecular level, allowing even transient tissue or nerve damage to elicit …

Chronic pain is a major medical problem that is resistant to conventional medical
intervention. It also causes emotional changes such as anxiety and fear. Furthermore …

Chronic pain can lead to anxiety and anxiety can enhance the sensation of pain.
Unfortunately, little is known about the synaptic mechanisms that mediate these re-enforcing …

Chronic pain patients exhibit increased anxiety, depression, and deficits in learning and
memory. Yet how persistent pain affects the key brain area regulating these behaviors, the …

The outbreak of Zika virus (ZIKV) and associated fetal microcephaly mandates efforts to
understand the molecular processes of infection. Related flaviviruses produce noncoding …