Beneficial and detrimental aspects of miRNAs as chief players in breast cancer: a comprehensive review

A Ismail, HA El-Mahdy, AI Abulsoud… - International Journal of …, 2023 - Elsevier
Breast cancer (BC) is the most common cancer in women and poses a serious threat to their
health. Despite familiarity with factors affecting its etiology, initiation, progression, treatment …

A structural view of miRNA biogenesis and function

AL Leitão, FJ Enguita - Non-coding RNA, 2022 - mdpi.com
Micro-RNAs (miRNAs) are a class of non-coding RNAs (ncRNAs) that act as post-
transcriptional regulators of gene expression. Since their discovery in 1993, they have been …

Recent advances on microneedle arrays-mediated technology in cancer diagnosis and therapy

V Alimardani, SS Abolmaali, AM Tamaddon… - Drug Delivery and …, 2021 - Springer
Regarding the increasing prevalence of cancer throughout the globe, the development of
novel alternatives for conventional therapies is inevitable to circumvent limitations such as …

Spatiotemporally controllable microRNA imaging in living cells via a near-infrared light-activated nanoprobe

X Zhao, L Zhang, W Gao, X Yu, W Gu… - ACS applied materials …, 2020 - ACS Publications
In situ spatiotemporal microRNA (miRNA) imaging in mammal cells plays an essential role
in illustrating its structures and biological functions. Herein, we proposed a near-infrared …

[HTML][HTML] Dual antisense oligonucleotide targeting miR-21/miR-155 synergize photodynamic therapy to treat triple-negative breast cancer and inhibit metastasis

M Shang, Y Wu, Y Wang, Y Cai, J Jin, Z Yang - Biomedicine & …, 2022 - Elsevier
Triple negative breast cancer (TNBC) is a greatly aggressive subtype of breast cancer with
high recurrence and mortality rates. Chemotherapy as a primary treatment for cancer is …

[HTML][HTML] Competitive endogenous network of lncRNA, miRNA, and mRNA in the chemoresistance of gastrointestinal tract adenocarcinomas

K Raziq, M Cai, K Dong, P Wang, J Afrifa… - Biomedicine & …, 2020 - Elsevier
Chemotherapy is one of the main therapeutic strategies used for gastrointestinal tract
adenocarcinomas (GTAs), but resistance to anticancer drugs is a substantial obstacle in …

[HTML][HTML] m (6) A demethylase ALKBH5 inhibits cell proliferation and the metastasis of colorectal cancer by regulating the FOXO3/miR-21/SPRY2 axis

X Wu, M Dai, J Li, J Cai, Z Zuo, S Ni… - American Journal of …, 2021 - ncbi.nlm.nih.gov
Objective: Colorectal cancer is a common malignancy worldwide. This research aimed to
investigate the role of α-ketoglutarate-dependent dioxygenase alkB homologue 5 (ALKBH5) …

Growth arrest‐specific transcript 5 represses endometrial cancer development by promoting antitumor function of tumor‐associated macrophages

J Tu, X Tan, Y Chen, Y Chen, Z Li, Y Zhang… - Cancer …, 2022 - Wiley Online Library
The tumor‐suppressor role of long noncoding RNA (lncRNA) growth arrest‐specific
transcript 5 (GAS5) has been proven in various types of cancer. However, the specific …

A miRNA stabilizing polydopamine nano-platform for intraocular delivery of miR-21-5p in glaucoma therapy

C Tan, F Jia, P Zhang, X Sun, Y Qiao, X Chen… - Journal of Materials …, 2021 - pubs.rsc.org
The elevation of intraocular pressure (IOP) is an important risk factor in the development of
primary open angle glaucoma (POAG), which is the main cause of irreversible vision loss …

MicroRNA-372 acts as a double-edged sword in human cancers

F Tajik, F Alian, M Yousefi, A Azadfallah, A Hoseini… - Heliyon, 2023 - cell.com
MicroRNAs (miRNAs or miRs) are non-coding, single-stranded, endogenous RNAs that
regulate various biological processes, most notably the pathophysiology of many human …