The presence of a patent foramen ovale (PFO) is implicated in the pathogenesis of a number
of medical conditions; however, the subject remains controversial and no official statements …

Strokes in young adults are reported as being uncommon, comprising 10%–15% of all
stroke patients. However, compared with stroke in older adults, stroke in the young has a …

Background Trials of patent foramen ovale (PFO) closure to prevent recurrent stroke have
been inconclusive. We investigated whether patients with cryptogenic stroke and …

Background Whether closure of a patent foramen ovale reduces the risk of recurrence of
ischemic stroke in patients who have had a cryptogenic ischemic stroke is unknown …

The aim of this updated guideline is to provide comprehensive and timely evidence-based
recommendations on the prevention of future stroke among survivors of ischemic stroke or …

Background The options for secondary prevention of cryptogenic embolism in patients with
patent foramen ovale are administration of antithrombotic medications or percutaneous …

Key Clinical Points Cryptogenic Stroke One quarter of patients with ischemic stroke have no
probable cause found after standard workup, including echocardiography, inpatient cardiac …

Objective: We aimed to create an index to stratify cryptogenic stroke (CS) patients with
patent foramen ovale (PFO) by their likelihood that the stroke was related to their PFO …

Contrary to trends in most other diseases, the average age of ischaemic stroke onset is
decreasing, owing to a rise in the incidence of stroke among'young'individuals (under 50 …

Importance Recent epidemiologic and therapeutic advances have transformed
understanding of the role of and therapeutic approach to patent foramen ovale (PFO) in …