Excitotoxicity is one of the most extensively studied processes of neuronal cell death, and
plays an important role in many central nervous system (CNS) diseases, including CNS …

Epilepsy is a devastating disease affecting more than 1% of the population. Yet, if one
considers the neurobiological substrates of this disease, what is revealed is an array of …

Clinical experience suggests that both hypothyroidism and stress interfere with mental
concentration and memory. This electrophysiological study examined the effect of …

Temporal lobe epilepsy (TLE) is the most common type of epilepsy in humans. The lithium-
pilocarpine model in rodents reproduces some of the main features of human TLE. Three …

NMDA and AMPA Receptors: Development and Status Epilepticus Page 1
PHYSIOLOGICAL RESEARCH • ISSN 0862-8408(print) • ISSN 1802-9973(online) © 2013 …

This study was designed to determine whether hippocampal neuronal AMPA (alpha-amino-
3-hydroxy-5-methylisoxazole-4-propionic acid) and NMDA (N-methyl-D-aspartate) mRNA …

The identification of connexins (Cxs) expressed in neuronal cells represents a crucial step
for understanding the direct communication between neurons and between neuron and glia …

The persistent unresponsiveness of many of the acquired epilepsies to traditional
antiseizure medications has motivated the search for prophylactic drug therapies that could …

Status epilepticus (SE) is typically defined as a prolonged self‐sustaining seizure or
repeated seizures showing an incomplete recovery between them. SE represents a medical …

This study compared temporal lobe epilepsy patients, along with kindled animals and self
sustained limbic status epilepticus (SSLSE) rats for parallels in hippocampal AMPA and …