Excess calorie intake and a sedentary lifestyle have made non-alcoholic fatty liver disease
(NAFLD) one of the fastest growing forms of liver disease of the modern world. It is …

Abstract Background and Objective: Epigenetic alterations are common events in clear cell
renal cell carcinoma (ccRCC), and protein arginine methyltransferase 1 (PRMT1) is an …

Abstract Treatment of glioblastoma (GBM) remains a challenge using conventional
chemotherapy, such as temozolomide (TMZ), and is often ineffective as a result of drug …

Metastasis is the leading cause of cancer-associated mortality. Although advances in the
targeted treatment and immunotherapy have improved the management of some cancers …

Sorafenib is the first approved systemic therapy for advanced hepatocellular carcinoma
(HCC) and is the first-line choice in clinic. Sustained activation of receptor tyrosine kinases …

Introduction: Heparin sulphate proteoglycans in the liver tumour microenvironment (TME)
are key regulators of cell signalling, modulated by sulfatase-2 (SULF2). SULF2 …

Statement of Retraction We, the Editors and Publisher of the journal Cell Cycle, have
retracted the following article: Wei-Qiang Li, Jian-Peng Zhang, Yan-Yu Wang, Xin-Zhen Li …

Mutations affect gene functions related to cancer behavior, including cell growth, metastasis,
and drug responses. Genome-wide profiling of cancer mutations and drug responses has …

Our study investigated the therapeutic potential of OKN-007 in the SOD1 G93A mouse
model of amyotrophic lateral sclerosis (ALS). The impact of OKN-007, known for its …

Cancer stem cells (CSCs) are involved in cancer recurrence and metastasis owing to their
self-renewal properties and drug-resistance capacity. Lipocalin-2 (Lcn2) of the lipocalin …