Mechanisms underlying biological effects of cruciferous glucosinolate-derived isothiocyanates/indoles: a focus on metabolic syndrome

M Esteve - Frontiers in Nutrition, 2020 - frontiersin.org
An inverse correlation between vegetable consumption and the incidence of cancer has
long been described. This protective effect is stronger when cruciferous vegetables are …

Dietary glucosinolates derived isothiocyanates: chemical properties, metabolism and their potential in prevention of Alzheimer's disease

F Khan, A Joshi, HP Devkota… - Frontiers in …, 2023 - frontiersin.org
Alzheimer's disease (AD) is the most prevalent form of dementia affecting millions of people
worldwide. It is a progressive, irreversible, and incurable neurodegenerative disorder that …

Nitrates and glucosinolates as strong determinants of the nutritional quality in rocket leafy salads

M Cavaiuolo, A Ferrante - Nutrients, 2014 - mdpi.com
Rocket is an important leafy vegetable crop and a good source of antioxidants and
anticancer molecules such as glucosinolates and other sulfur compounds. Rocket is also a …

The functional role of sulforaphane in intestinal inflammation: a review

LY Wei, JK Zhang, L Zheng, Y Chen - Food & Function, 2022 - pubs.rsc.org
Intestinal inflammation represented by inflammatory bowel disease (IBD) has become a
global epidemic disease and the number of patients with IBD continues to increase. This …

Natural Nrf2 modulators for skin protection

YC Boo - Antioxidants, 2020 - mdpi.com
Since the discovery of antioxidant responsive elements (ARE), which are commonly found in
the promoter of the Phase II metabolism/antioxidant enzymes, and nuclear factor erythroid 2 …

Nrf2 activation attenuates acrylamide-induced neuropathy in mice

CB Davuljigari, FA Ekuban, C Zong… - International journal of …, 2021 - mdpi.com
Acrylamide is a well characterized neurotoxicant known to cause neuropathy and
encephalopathy in humans and experimental animals. To investigate the role of nuclear …

Chemical composition, traditional and professional use in medicine, application in environmental protection, position in food and cosmetics industries, and …

M Klimek-Szczykutowicz, A Szopa, H Ekiert - Fitoterapia, 2018 - Elsevier
The herb of Nasturtium officinale is a raw material that has long been used in the traditional
medicine of Iran, Azerbaijan, Morocco and Mauritius. Nowadays, this raw material is the …

The influence of different wavelengths of LED light on the production of glucosinolates and phenolic compounds and the antioxidant potential in in vitro cultures of …

M Klimek-Szczykutowicz, B Prokopiuk… - Plant Cell, Tissue and …, 2022 - Springer
Cultures of Nasturtium officinale were cultivated in vitro under illumination with different
wavelengths of light-emitting diode (LED) light (white LED light—WLED, blue light—B, red …

Allyl isothiocyanate attenuates oxidative stress and inflammation by modulating Nrf2/HO-1 and NF-κB pathways in traumatic brain injury in mice

B Caglayan, E Kilic, A Dalay, S Altunay, M Tuzcu… - Molecular biology …, 2019 - Springer
Traumatic brain injury (TBI) is the leading cause of mortality and morbidity in young adults
and children in the industrialized countries; however, there are presently no FDA approved …

DSS-induced acute colitis in C57BL/6 mice is mitigated by sulforaphane pre-treatment

AE Wagner, O Will, C Sturm, S Lipinski… - The Journal of nutritional …, 2013 - Elsevier
The Brassica-derived isothiocyanate sulforaphane (SFN) is known to induce factor erythroid
2-related factor 2 (Nrf2), a transcription factor centrally involved in chemoprevention …