Non-coding RNAs in disease: from mechanisms to therapeutics
Non-coding RNAs (ncRNAs) are a heterogeneous group of transcripts that, by definition, are
not translated into proteins. Since their discovery, ncRNAs have emerged as important …
not translated into proteins. Since their discovery, ncRNAs have emerged as important …
A comprehensive SARS-CoV-2 and COVID-19 review, Part 2: host extracellular to systemic effects of SARS-CoV-2 infection
SA Narayanan, DA Jamison Jr, JW Guarnieri… - European Journal of …, 2024 - nature.com
COVID-19, the disease caused by SARS-CoV-2, has caused significant morbidity and
mortality worldwide. The betacoronavirus continues to evolve with global health implications …
mortality worldwide. The betacoronavirus continues to evolve with global health implications …
Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral proteins bind to host
mitochondrial proteins, likely inhibiting oxidative phosphorylation (OXPHOS) and stimulating …
mitochondrial proteins, likely inhibiting oxidative phosphorylation (OXPHOS) and stimulating …
Engineered LwaCas13a with enhanced collateral activity for nucleic acid detection
Clustered regularly interspaced short palindromic repeats (CRISPR)–CRISPR-associated
protein 13 (Cas13) has been rapidly developed for nucleic-acid-based diagnostics by using …
protein 13 (Cas13) has been rapidly developed for nucleic-acid-based diagnostics by using …
[HTML][HTML] Circulating microRNAs as emerging regulators of COVID-19
Y Liang, D Fang, X Gao, X Deng, N Chen, J Wu… - Theranostics, 2023 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19), an infectious disease caused by the novel
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a global pandemic that …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a global pandemic that …
MiRNA-SARS-CoV-2 dialogue and prospective anti-COVID-19 therapies
COVID-19 is a highly transmissible disease caused by severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2), affects 226 countries and continents, and has resulted in> 6.2 …
coronavirus-2 (SARS-CoV-2), affects 226 countries and continents, and has resulted in> 6.2 …
sChemNET: a deep learning framework for predicting small molecules targeting microRNA function
MicroRNAs (miRNAs) have been implicated in human disorders, from cancers to infectious
diseases. Targeting miRNAs or their target genes with small molecules offers opportunities …
diseases. Targeting miRNAs or their target genes with small molecules offers opportunities …
Drugs for COVID-19: An update
J Ceramella, D Iacopetta, MS Sinicropi, I Andreu… - Molecules, 2022 - mdpi.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was the seventh
known human coronavirus, and it was identified in Wuhan, Hubei province, China, in 2020. It …
known human coronavirus, and it was identified in Wuhan, Hubei province, China, in 2020. It …
Non-coding RNAs expression in SARS-CoV-2 infection: pathogenesis, clinical significance, and therapeutic targets
X Liu, W Xiong, M Ye, T Lu, K Yuan, S Chang… - … and Targeted Therapy, 2023 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has been looming globally for
three years, yet the diagnostic and treatment methods for COVID-19 are still undergoing …
three years, yet the diagnostic and treatment methods for COVID-19 are still undergoing …
A differential signature of circulating miRNAs and cytokines between COVID-19 and community-acquired pneumonia uncovers novel physiopathological mechanisms …
P Martínez-Fleta, P Vera-Tomé… - Frontiers in …, 2022 - frontiersin.org
Coronavirus Disease 2019 (COVID-19) pneumonia is a life-threatening infectious disease,
especially for elderly patients with multiple comorbidities. Despite enormous efforts to …
especially for elderly patients with multiple comorbidities. Despite enormous efforts to …