1, 25-Dihydroxvitamin D3 [1, 25 (OH) 2D3] is the hormonally active form of vitamin D. The
genomic mechanism of 1, 25 (OH) 2D3 action involves the direct binding of the 1, 25 (OH) …

A low vitamin D status is associated with an increased risk of various cancers, such as of
colon, breast, prostate and hematological cells. The biologically most active vitamin D …

Vitamin D is not really a vitamin but the precursor to the potent steroid hormone calcitriol,
which has widespread actions throughout the body. Calcitriol regulates numerous cellular …

This is a narrative review of the evidence supporting vitamin D's anticancer actions. The first
section reviews the findings from ecological studies of cancer with respect to indices of solar …

Uncontrolled overgrowth of cells, such as in cancer, is an unavoidable risk in life that affects
nearly every second individual in industrialized countries. However, in part this risk can be …

Colorectal cancer (CRC) is the neoplasia that is most frequently associated with vitamin D
deficiency in epidemiological and observational studies in terms of incidence and mortality …

In many cells throughout the body, vitamin D is converted into its active form calcitriol and
binds to the vitamin D receptor (VDR), which functions as a transcription factor to regulate …

In the last two decades vitamin D (VD) research has demonstrated new extraskeletal actions
of this pre-hormone, suggesting a protective role of this secosteroid in the onset, progression …

The seasonality of infectious disease outbreaks suggests that environmental conditions
have a significant effect on disease risk. One of the major environmental factors that can …

Bile acids (BAs) regulate the absorption of fat-soluble vitamins, cholesterol and lipids but
have also a key role as signaling molecules and in the modulation of epithelial cell …