Cancer is one of the major diseases threatening human life and health worldwide.
Epigenetic modification refers to heritable changes in the genetic material without any …

Cellular RNAs, both coding and noncoding are adorned by> 100 chemical modifications,
which impact various facets of RNA metabolism and gene expression. Very often …

Aberrant expression of methyltransferases and demethylases may augment tumor initiation,
proliferation and metastasis through RNA modification, such as m6A and m5C. However …

Background Clear cell renal cell carcinoma (ccRCC) displays sex-biased incidence,
outcomes, molecular alterations and treatment efficacy; however, clinical managements are …

In the past few decades, advances in the outcomes of patients suffering from pancreatic
ductal adenocarcinoma (PDAC) have lagged behind these gained in the treatment of many …

The role of non‑SMC condensin I complex subunit G (NCAPG) in breast cancer remains
unclear. The present study used online databases, reverse transcription‑quantitative PCR …

Aim Artificial intelligence (AI)‐based breast cancer grading may help to overcome perceived
limitations of human assessment. Here, the potential value of AI grade was evaluated at the …

Nucleic acid modifications include a wide range of epigenetic and epitranscriptomic factors
and impact a wide range of nucleic acids due to their profound influence on biological …

Dyskerin and its homologs are ancient and conserved enzymes that catalyze the most
common post-transcriptional modification found in cells, pseudouridylation. The resulting …

Simple Summary Aberrant alternative splicing is now considered a hallmark of cancer,
including breast cancer. This results in the production of novel tumor-specific splice RNA …