Chemotherapy-induced damage to ovary: mechanisms and clinical impact

G Bedoschi, PA Navarro, K Oktay - Future oncology, 2016 - Taylor & Francis
Cancer is a major public health problem around the world. Currently, about 5% of women
diagnosed with cancer are of reproductive age. These young survivors may face …

Individualization of controlled ovarian stimulation in IVF using ovarian reserve markers: from theory to practice

A La Marca, SK Sunkara - Human reproduction update, 2014 - academic.oup.com
BACKGROUND The main objective of individualization of treatment in IVF is to offer every
single woman the best treatment tailored to her own unique characteristics, thus maximizing …

Impairment of BRCA1-related DNA double-strand break repair leads to ovarian aging in mice and humans

S Titus, F Li, R Stobezki, K Akula, E Unsal… - Science translational …, 2013 - science.org
The underlying mechanism behind age-induced wastage of the human ovarian follicle
reserve is unknown. We identify impaired ATM (ataxia-telangiectasia mutated)–mediated …

[HTML][HTML] Prediction of an excessive response in in vitro fertilization from patient characteristics and ovarian reserve tests and comparison in subgroups: an individual …

SL Broer, M Dólleman, J Van Disseldorp, KA Broeze… - Fertility and sterility, 2013 - Elsevier
Objective To evaluate whether ovarian reserve tests (ORTs) add prognostic value to patient
characteristics, such as female age, in the prediction of excessive response to ovarian …

Current and future perspectives for improving ovarian tissue cryopreservation and transplantation outcomes for cancer patients

S Lee, S Ozkavukcu, SY Ku - Reproductive Sciences, 2021 - Springer
Although advances in cancer treatment and early diagnosis have significantly improved
cancer survival rates, cancer therapies can cause serious side effects, including ovarian …

[HTML][HTML] Preserving fertility in female patients with hematological malignancies: a multidisciplinary oncofertility approach

M Salama, A Anazodo, TK Woodruff - Annals of Oncology, 2019 - Elsevier
Oncofertility is a new interdisciplinary field at the intersection of oncology and reproductive
medicine that expands fertility options for young cancer patients. The most common forms of …

State of the art on oocyte cryopreservation in female cancer patients: a critical review of the literature

C Massarotti, P Scaruffi, M Lambertini… - Cancer treatment …, 2017 - Elsevier
During the last decades, important advances in therapeutic options have led to increased
survival rates in cancer patients; however, cancer treatments are associated with several …

[HTML][HTML] Fertility preservation and breast cancer: a review

M De Pedro, B Otero, B Martín - ecancermedicalscience, 2015 - ncbi.nlm.nih.gov
Breast cancer is the most common malignancy in women, and its incidence increases with
age, with the majority of patients diagnosed after menopause. However, in 15–25% of …

Anti-Müllerian hormone and assessment of ovarian reserve after ovarian toxic treatment: a systematic narrative review

A Iwase, T Nakamura, T Nakahara… - Reproductive …, 2015 - journals.sagepub.com
Since serum anti-Müllerian hormone (AMH) levels enable quantitative evaluation of ovarian
damage, we conducted a computer-based search, using key words, of all articles published …

Oocyte and embryo cryopreservation before gonadotoxic treatments: Principles of safe ovarian stimulation, a systematic review

MCH Ozcan, V Snegovskikh… - Women's Health, 2022 - journals.sagepub.com
Objective: Review the safety of fertility preservation through ovarian stimulation with oocyte
or embryo cryopreservation, including cycle and medication options. Evidence review: A …