[HTML][HTML] Targeting β-cell plasticity: A promising approach for diabetes treatment

E Ghasemi Gojani, S Rai, F Norouzkhani… - Current Issues in …, 2024 - mdpi.com
The β-cells within the pancreas play a pivotal role in insulin production and secretion,
responding to fluctuations in blood glucose levels. However, factors like obesity, dietary …

[HTML][HTML] Role of epigenetic mechanisms in the pathogenesis of chronic respiratory diseases and response to inhaled exposures: From basic concepts to clinical …

RZ Jurkowska - Pharmacology & Therapeutics, 2024 - Elsevier
Epigenetic modifications are chemical groups in our DNA (and chromatin) that determine
which genes are active and which are shut off. Importantly, they integrate environmental …

In vivo models of gestational and type 2 diabetes mellitus characterized by endocrine pancreas cell impairments

SK Szlapinski, DJ Hill - Journal of Endocrinology, 2024 - joe.bioscientifica.com
Insulin resistance contributes to the development of various diseases, including type 2
diabetes and gestational diabetes. Even though gestational diabetes is specific to …

The genome in space and time comes of age

M Rey-Millet, K Bystricky… - 2024 - Taylor & Francis
ABSTRACT DNA sequencing is not enough to grasp the complexity of genome organization
and function. The four-dimensional (three in space, one in time) configuration of the …

Personalized epigenetic management of diabetes

D Sapehia, N Bhardwaj, H Goyal, A Mahajan… - Personalized …, 2024 - Elsevier
Diabetes is a complex metabolic disorder characterized by high blood glucose levels
resulting from impaired insulin secretion, insulin resistance, or both. Emerging evidence …

[引用][C] Uloga ciljanih (epi) genetičkih modifikacija u potencijalnoj terapiji dijabetesa

M Đorđević, S Dinić… - Trendovi u …, 2023 - Beograd: Institut za molekularnu …