The Prevalence of Low-level Viraemia and Its Association with Virological Failure in People Living With HIV: A Systematic Review and Meta-Analysis

S Zhao, W Wang, S Li, J He, W Duan… - Emerging Microbes & …, 2024 - Taylor & Francis
Low-level viraemia (LLV) following antiretroviral therapy (ART) in people living with HIV
(PLWH) has not received sufficient attention. To the determine the prevalence of LLV and its …

Temporal dynamics and drivers of durable HIV viral load suppression and persistent high‐and low‐level viraemia during Universal Test and Treat scale‐up in Uganda …

JG Rosen, R Ssekubugu, LW Chang… - Journal of the …, 2024 - Wiley Online Library
Introduction Population‐level data on durable HIV viral load suppression (VLS) following the
implementation of Universal Test and Treat (UTT) in Africa are limited. We assessed trends …

Longitudinal viral load outcomes of adults with HIV after detectable viremia on tenofovir, lamivudine, and dolutegravir

O Sodeke, K Milligan, I Ezeuko, A Oladipo, A Emeh… - AIDS, 2024 - journals.lww.com
Background: To inform optimal management of HIV viremia on tenofovir, lamivudine, and
dolutegravir (TLD), we examined viral load (VL) outcomes of a large cohort of adult PWH on …

The virological consequences of low-level viraemia

BO Olakunde, EE Ezeanolue - The Lancet Global Health, 2022 - thelancet.com
With highly active antiretroviral therapy (ART), people living with HIV can achieve and
maintain viral suppression below a detectable level, preventing transmission of HIV and …

Detectable Virological Load and Associated Factors among People Living with HIV on Antiretroviral Treatment: A Retrospective Study

P Congedo, R Sedile, M Guido, F Banchelli, A Zizza - Pathogens, 2024 - mdpi.com
The complete and prolonged suppression of viral load is the primary objective of HAART in
people living with HIV. Some people may experience therapeutic failure, while others may …

Incidence of low-level viremia and its impact on virologic failure among people living with HIV who started an integrase strand transfer inhibitors: a longitudinal cohort …

X Lao, H Zhang, M Deng, Q Li, Q Xiao, L He… - BMC Infectious …, 2024 - Springer
Background Low-level viremia (LLV) has been identified as a potential precursor to virologic
failure (VF), yet its clinical implications, particularly within the context of Integrase Strand …

Prevalence and predictors of persistent low-level HIV viraemia: a retrospective cohort study among people receiving dolutegravir-based antiretroviral therapy in …

O Onwah, E Nwanja, U Akpan, O Toyo… - Therapeutic …, 2024 - journals.sagepub.com
Background: Persistent low-level viraemia (PLLV) is a risk factor for virologic failure among
people receiving antiretroviral therapy (ART). Objectives: We assessed the prevalence and …

Low-Level Viremia among Adults Living with HIV on Dolutegravir-Based First-Line Antiretroviral Therapy Is a Predictor of Virological Failure in Botswana

OT Bareng, S Moyo, M Mudanga, K Sebina… - Viruses, 2024 - mdpi.com
We evaluated subsequent virologic outcomes in individuals experiencing low-level virem ia
(LLV) on dolutegravir (DTG)-based first-line antiretroviral therapy (ART) in Botswana. We …

HIV risk behaviour, viraemia, and transmission across HIV cascade stages including low-level viremia: Analysis of 14 cross-sectional population-based HIV Impact …

O Edun, L Okell, H Chun, ACZ Bissek… - PLOS Global Public …, 2024 - journals.plos.org
As antiretroviral treatment (ART) coverage for people living with HIV (PLHIV) increases, HIV
programmes require up-to-date information about evolving HIV risk behaviour and …

Prevalence of HIV drug resistance among adolescents receiving ART in Cameroon with low-or high-level viraemia

ABD Djiyou, CI Penda, Y Madec… - Journal of …, 2023 - academic.oup.com
Objectives To characterize HIV drug resistance (HIVDR) below and above the WHO
threshold of 1000 copies/mL, considered for the definition of HIV ART failure in resource …