Background Bloodstream infections are a major cause of death with increasing incidence
and severity. Blood cultures are still the reference standard for microbiological diagnosis, but …

Invasive infections caused by members of the genus Candida are on the rise. Especially
patients in intensive care units, immunocompromised patients, and those recovering from …

Background Our current understanding of the pathophysiology and management of sepsis is
associated with a lack of progress in clinical trials, which partly reflects insufficient …

Despite the scientific advances observed in the recent decades and the emergence of new
methodologies, the diagnosis of systemic fungal infections persists as a problematic issue …

脓毒症是威胁人类健康的急危重症之一, 其发病后的致残率及致死率均处于较高水平,
早期发现并尽早治疗脓毒症可以有效降低这一比例. 因此, 对脓毒症的早期判别已成为国际共识 …

Microorganisms, encompassing both uni-and multicellular entities, exhibit remarkable
diversity as omnipresent life forms in nature. They play a pivotal role by supplying essential …

Introduction: The antimicrobial aspect of management of patients with blood stream
infections (BSI) and sepsis is time critical. In an era of increasing antimicrobial resistance …

Introduction: Fungemia presents high morbi-mortality and thus rapid microbiological
diagnosis may contribute to appropriate patient management. In the last decade, kits based …

ABSTRACT Introduction Methicillin-resistant Staphylococcus aureus (MRSA) is associated
with adverse clinical outcomes and increased morbidity, mortality, length of hospital stay …

Combination of strategies for rapid diagnostics tests (RDT) with real-time intervention could
improve patient outcomes. We aimed to assess the impact on clinical outcomes …