G Chandra, A Pandey - Biocybernetics and Biomedical Engineering, 2020 - Elsevier
A biologically-validated biodegradable material must comfortably stay in the physiological environment it is placed in, before finally disappearing over the intended period of time with …
Fracture healing is a specialized post‐natal repair process that recapitulates aspects of embryological skeletal development. While many of the molecular mechanisms that control …
The skeleton is an efficient'servo'(feedback-controlled/steady-state) system that continuously integrates signals and responses which sustain its functions of delivering calcium while …
RAD Carano, EH Filvaroff - Drug discovery today, 2003 - Elsevier
The intimate connection, both physical and biochemical, between blood vessels and bone cells has long been recognized. Genetic, biochemical, and pharmacological studies have …
The present work utilizes electrospinning to fabricate synthetic polymer/DNA composite scaffolds for therapeutic application in gene delivery for tissue engineering. The scaffolds …
Research in polymer nanofibers has undergone significant progress in the last one decade. One of the main driving forces for this progress is the increasing use of these polymer …
K Arvidson, BM Abdallah, LA Applegate… - Journal of cellular …, 2011 - Wiley Online Library
Introduction• Bone fracture healing and healing problems• Biomaterial scaffolds and tissue engineering in bone formation‐Bone tissue engineering‐Biomaterial scaffolds‐Synthetic …
Recent revelations that the canonical Wnt signaling pathway promotes postnatal bone accrual are major advances in our understanding of skeletal biology and bring tremendous …
P Kostenuik, FM Mirza - Journal of Orthopaedic Research®, 2017 - Wiley Online Library
Delayed healing and nonunion of fractures represent enormous burdens to patients and healthcare systems. There are currently no approved pharmacological agents for the …