Conservation between the RNA polymerase I, II, and III transcription initiation machineries
A Vannini, P Cramer - Molecular cell, 2012 - cell.com
Recent studies of the three eukaryotic transcription machineries revealed that all initiation
complexes share a conserved core. This core consists of the RNA polymerase (I, II, or III), the …
complexes share a conserved core. This core consists of the RNA polymerase (I, II, or III), the …
Transcriptional Regulation in Saccharomyces cerevisiae: Transcription Factor Regulation and Function, Mechanisms of Initiation, and Roles of Activators and …
S Hahn, ET Young - Genetics, 2011 - academic.oup.com
Here we review recent advances in understanding the regulation of mRNA synthesis in
Saccharomyces cerevisiae. Many fundamental gene regulatory mechanisms have been …
Saccharomyces cerevisiae. Many fundamental gene regulatory mechanisms have been …
Molecular structures of unbound and transcribing RNA polymerase III
Transcription of genes encoding small structured RNAs such as transfer RNAs,
spliceosomal U6 small nuclear RNA and ribosomal 5S RNA is carried out by RNA …
spliceosomal U6 small nuclear RNA and ribosomal 5S RNA is carried out by RNA …
Interrogation of mammalian protein complex structure, function, and membership using genome-scale fitness screens
Protein complexes are assemblies of subunits that have co-evolved to execute one or many
coordinated functions in the cellular environment. Functional annotation of mammalian …
coordinated functions in the cellular environment. Functional annotation of mammalian …
Structural basis of RNA polymerase III transcription initiation
RNA polymerase (Pol) III transcribes essential non-coding RNAs, including the entire pool of
transfer RNAs, the 5S ribosomal RNA and the U6 spliceosomal RNA, and is often …
transfer RNAs, the 5S ribosomal RNA and the U6 spliceosomal RNA, and is often …
Crystal structure of the 14-subunit RNA polymerase I
C Fernández-Tornero, M Moreno-Morcillo, UJ Rashid… - Nature, 2013 - nature.com
Protein biosynthesis depends on the availability of ribosomes, which in turn relies on
ribosomal RNA production. In eukaryotes, this process is carried out by RNA polymerase I …
ribosomal RNA production. In eukaryotes, this process is carried out by RNA polymerase I …
The La and related RNA‐binding proteins (LARPs): structures, functions, and evolving perspectives
RJ Maraia, S Mattijssen… - Wiley Interdisciplinary …, 2017 - Wiley Online Library
La was first identified as a polypeptide component of ribonucleic protein complexes targeted
by antibodies in autoimmune patients and is now known to be a eukaryote cell‐ubiquitous …
by antibodies in autoimmune patients and is now known to be a eukaryote cell‐ubiquitous …
Molecular mechanism of promoter opening by RNA polymerase III
Abstract RNA polymerase III (Pol III) and transcription factor IIIB (TFIIIB) assemble together
on different promoter types to initiate the transcription of small, structured RNAs. Here we …
on different promoter types to initiate the transcription of small, structured RNAs. Here we …
Transcription termination by the eukaryotic RNA polymerase III
RNA polymerase (pol) III transcribes a multitude of tRNA and 5S rRNA genes as well as
other small RNA genes distributed through the genome. By being sequence-specific …
other small RNA genes distributed through the genome. By being sequence-specific …
[HTML][HTML] The initiation factor TFE and the elongation factor Spt4/5 compete for the RNAP clamp during transcription initiation and elongation
D Grohmann, J Nagy, A Chakraborty, D Klose… - Molecular cell, 2011 - cell.com
TFIIE and the archaeal homolog TFE enhance DNA strand separation of eukaryotic RNAPII
and the archaeal RNAP during transcription initiation by an unknown mechanism. We have …
and the archaeal RNAP during transcription initiation by an unknown mechanism. We have …