Abstract MicroRNAs (miRNAs), small non-coding RNAs (ncRNAs) of about 22 nucleotides in
size, play important roles in gene regulation, and their dysregulation is implicated in human …

MicroRNAs (miRNAs) are small non-coding RNAs with a length of about 19–25 nt, which
can regulate various target genes and are thus involved in the regulation of a variety of …

Pyroptosis, a newly characterized form of immunogenic cell death, is attracting increasing
attention as a promising approach to cancer immunotherapy. However, biocompatible …

Overcoming apoptosis resistance to achieve efficient breast cancer treatment remains a
challenge. The precise induction of another form of programmed cell death, pyroptosis, is an …

Single therapy for tumor therapy always exerts limited ability for the constraints on the
reaction condition and the unavoidable multidrug resistance, which seriously influences the …

Pyroptosis as a lytic and inflammatory form of cell death is a powerful tool to fight against
cancer. However, pyroptosis is usually activated by chemotherapeutic drugs, which limits its …

Cancer represents a group of heterogeneous diseases characterized by uncontrolled
growth and spread of abnormal cells, ultimately leading to death. Nanomedicine plays a …

Multidrug resistance (MDR) is the dominant cause of the failure of cancer chemotherapy.
The design of antitumor drugs that are able to evade MDR is rapidly evolving, showing that …

Multidrug resistance (MDR) is a serious phenomenon employed by cancer cells which
hampers the success of cancer pharmacotherapy. One of the common mechanisms of MDR …

Immunotherapy shows remarkable efficacy in treating several types of cancer such as
melanoma, leukemia, and lung carcinoma, but its therapeutic effect for most solid tumors is …