[HTML][HTML] Synthesis and antibacterial activity of angular tetrahydrocycloamino [1, 2-a] quinoxalin-4-one derivatives

JA Odusami, MI Ikhile, IA Olasupo, MCD Fotsing… - Scientific African, 2024 - Elsevier
Objectives The resistance of bacteria to current antibiotics is a significant concern in treating
infectious diseases, posing a strong threat to global health, food security, and development …

Synthesis of substituted N-(2′-nitrophenyl) pyrrolidine-2-carboxamides towards the design of proline-rich antimicrobial peptide mimics to eliminate bacterial …

JA Odusami, MI Ikhile, JU Izunobi, IA Olasupo… - Bioorganic …, 2020 - Elsevier
The treatment of diseases is under threat due to the increasing resistance of disease-
causing bacteria to antibiotics. Likewise, free radical-induced oxidative stress has been …

N-Aryl Amino Acids as Potential Antibacterial Agents

AD Osinubi, OT Asekun, OB Familoni - Reactions, 2023 - mdpi.com
The resistance of bacteria to current antibiotic drugs and the re-occurrence of different
ailments after several therapeutic protocols continue to be a cause for concern. Arylated …

Synthesis and in vitro anticancer activities of substituted N-(4′-nitrophenyl)-l-prolinamides

A Osinubi, J Izunobi, X Bao… - Royal Society …, 2020 - royalsocietypublishing.org
Prolinamides are present in secondary metabolites and have wide-ranging biological
properties as well as antimicrobial and cytotoxic activities. N-(4′-substituted phenyl)-l …

Transition Metal‐Free, Base‐Induced Arylation of Amino Acids: Synthesis of N‐(para‐Substituted phenyl)amino‐2‐carboxylic acids

AD Osinubi, JU Izunobi, OT Asekun… - …, 2020 - Wiley Online Library
A metal‐free aryl amination reaction of aryl halides and amino acids; with the amino acid
serving as the nucleophilic aminating agent, is reported. The reaction was achieved by the …

N-(4-Substituted Aryl) amino acids as potential antibacterial agents

A Osinubi, O Asekun, O Familoni - 2023 - researchsquare.com
Resistance of bacteria to current antibiotic drugs and the reoccurrence of different ailments
after several therapeutic protocols have continued to be a cause of concern. Arylated amino …

The Method of Antibiotic Potency Measurement Based on Image Processing

D Zhu - International Conference on Multi-modal Information …, 2022 - Springer
With the development of social economy, antibiotics have an increasing impact on people's
lives and agricultural production. The antibiotic dose is usually expressed by the potency …