Neuropsychiatric (NP) events occur in the majority of patients with SLE and predominantly
affect the CNS in addition to the peripheral and autonomic systems. Approximately 30% of …

Neuropsychiatric lupus (NPSLE) is a debilitating manifestation of SLE which occurs in a
majority of SLE patients and has a variety of clinical manifestations. In the central nervous …

Objectives To examine the association between blood-brain barrier (BBB) integrity, brain
volume and cognitive dysfunction in adult patients with systemic lupus erythematosus (SLE) …

Introduction Juvenile-onset systemic lupus erythematosus (JSLE) is a rare autoimmune/
inflammatory disease with significant morbidity and mortality. Neuropsychiatric (NP) …

Early diagnosis is currently the most effective way of saving the life of patients with
neuropsychiatric systemic lupus erythematosus (NPSLE). However, it is rather difficult to …

Objective To phenotype SLE based on symptom burden (disease damage, system
involvement and patient reported outcomes), with a specific focus on objective and …

Abstract Purpose of Review To report a series of patients with clinical and radiological
features suggestive of posterior reversible encephalopathy syndrome (PRES) related to …

Inflammatory disorders of the central nervous system (CNS) vessels, also called CNS
vasculitides, can cause substantial disability or even be fatal. Inflammation of the CNS …

Patients with systemic lupus erythematosus (SLE) frequently suffer from nervous system
complications, termed neuropsychiatric lupus erythematosus (NPLE). NPLE accounts for the …

Objectives Interferon-alpha, an important contributor to SLE pathogenesis, induces the
enzyme indoleamine 2, 3-dioxygenase in the kynurenine/tryptophan (KYN/TRP) pathway …