[HTML][HTML] Splicing and beyond: the many faces of the Prp19 complex

S Chanarat, K Sträßer - Biochimica et Biophysica Acta (BBA)-Molecular …, 2013 - Elsevier
Abstract The conserved Prp19 complex (Prp19C)—also known as NineTeen Complex
(NTC)—functions in several processes of paramount importance for cellular homeostasis …

The spliceosome-activating complex: molecular mechanisms underlying the function of a pleiotropic regulator

C Koncz, F Dejong, N Villacorta, D Szakonyi… - Frontiers in plant …, 2012 - frontiersin.org
Correct interpretation of the coding capacity of RNA polymerase II transcribed eukaryotic
genes is determined by the recognition and removal of intronic sequences of pre-mRNAs by …

Single-cell RNA-seq analysis of cells from degenerating and non-degenerating intervertebral discs from the same individual reveals new biomarkers for intervertebral …

H Cherif, M Mannarino, AS Pacis, J Ragoussis… - International journal of …, 2022 - mdpi.com
In this study, we used single-cell transcriptomic analysis to identify new specific biomarkers
for nucleus pulposus (NP) and inner annulus fibrosis (iAF) cells, and to define cell …

ZRANB2 and SYF2-mediated splicing programs converging on ECT2 are involved in breast cancer cell resistance to doxorubicin

I Tanaka, A Chakraborty, O Saulnier… - Nucleic acids …, 2020 - academic.oup.com
Besides analyses of specific alternative splicing (AS) variants, little is known about AS
regulatory pathways and programs involved in anticancer drug resistance. Doxorubicin is …

Overexpression of SYF2 correlates with enhanced cell growth and poor prognosis in human hepatocellular carcinoma

S Zhang, W Shi, Y Chen, Z Xu, J Zhu, T Zhang… - Molecular and cellular …, 2015 - Springer
SYF2, also known as p29/NTC31/CBPIN, encodes a nuclear protein that interacts with
Cyclin D-type binding-protein 1. SYF2 has been reported to be involved in pre-mRNA …

hPuf-A/KIAA0020 modulates PARP-1 cleavage upon genotoxic stress

HY Chang, CC Fan, PC Chu, BE Hong, HJ Lee… - Cancer research, 2011 - AACR
Abstract Human hPuf-A/KIAA0020 was first identified as a new minor histocompatibility
antigen in 2001. Its zebrafish orthologue contains six Pumilio-homology RNA-binding …

Disruption of Murine mp29/Syf2/Ntc31 Gene Results in Embryonic Lethality with Aberrant Checkpoint Response

CH Chen, PC Chu, L Lee, HW Lien, TL Lin, CC Fan… - PLoS …, 2012 - journals.plos.org
Human p29 is a putative component of spliceosomes, but its role in pre-mRNA is elusive. By
siRNA knockdown and stable overexpression, we demonstrated that human p29 is involved …

[HTML][HTML] Overexpression of SYF2 promotes cell proliferation and correlates with poor prognosis in human breast cancer

F Shi, FF Cai, L Cai, XY Lin, W Zhang, QQ Wang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
SYF2, a known cell cycle regulator, is reported to be involved in cell cycle arrest by
interacting with cyclin-D-type binding protein 1. In the present study, we investigated the role …

Genome-wide identification and functional analysis of the splicing component SYF2/NTC31/p29 across different plant species

Y Tian, MX Chen, JF Yang, HHK Achala, B Gao… - Planta, 2019 - Springer
Main conclusion This study systematically identifies plant SYF2/NTC31/p29 genes from 62
plant species by a combinatory bioinformatics approach, revealing the importance of this …

Upregulation of SYF2 is associated with neuronal apoptosis caused by reactive astrogliosis to neuroinflammation

W Xu, M Cao, H Zheng, X Tan, L Li… - Journal of …, 2014 - Wiley Online Library
SYF2, known as CCNDBP1‐interactor or p29, is likely involved in pre‐mRNA splicing and
cell cycle progression. The present study was designed to elucidate dynamic changes in …