Mitochondria are recognized as one of the most important targets for new drug design in
cancer, cardiovascular, and neurological diseases. Currently, the most effective way to …

Collaborative efforts from the fields of biology, materials science, and engineering are
leading to exciting progress in the development of nanomedicines. Since the targets of many …

Mitochondria are the powerhouse of cells. They are vital organelles that maintain cellular
function and metabolism. Dysfunction of mitochondria results in various diseases with a …

Nanoparticles can be engineered with distinctive composition, size, shape, and surface
chemistry to enable novel techniques in a wide range of biological applications. The unique …

Highlights•Mitochondria are involved in various physiochemical and biochemical
processes.•Owing to their crucial role in cellular metabolism, mitochondria are favored …

Mitochondrial dysfunctions cause numerous human disorders. A platform technology based
on biodegradable polymers for carrying bioactive molecules to the mitochondrial matrix …

Previously, stearyl triphenylphosphonium (STPP)-modified liposomes (STPP-L) were
reported to target mitochondria. To overcome a non-specific cytotoxicity of STPP-L, we …

Mitochondria are a novel and promising therapeutic target for diagnosis, treatment and
prevention of a lot of human diseases such as cancer, metabolic diseases and …

Sclareol, a diterpene alcohol isolated from the herbal and flavor plant clary sage (Salvia
sclarea L.), is far-famed as the predominant ingredient in the refined oil of Salvia sclarea (L.) …

Dendrimers have emerged as promising carriers for the delivery of a wide variety of pay-
loads including therapeutic drugs, imaging agents and nucleic acid materials into biological …