Clinical pharmacology of nonsteroidal anti-inflammatory drugs in dogs

B KuKanich, T Bidgood, O Knesl - Veterinary anaesthesia and analgesia, 2012 - Elsevier
Objectives To discuss the clinical pharmacology of currently licensed veterinary NSAIDs and
to review gastrointestinal and renal adverse effects as well as drug-drug interactions that …

Bovine dehorning: Assessing pain and providing analgesic management

ML Stock, SL Baldridge, D Griffin… - … Clinics: Food Animal …, 2013 - vetfood.theclinics.com
Dehorning is a commonly performed practice in both beef and dairy cattle industries.
Dehorning or disbudding in cattle is performed for a variety of reasons, including safety for …

2015 AAHA/AAFP pain management guidelines for dogs and cats

ME Epstein, I Rodanm, G Griffenhagen… - Journal of feline …, 2015 - journals.sagepub.com
Rationale: The robust advances in pain management for companion animals underlie the
decision of the American Animal Hospital Association (AAHA) and American Association of …

Opioids

B KuKanich, AJ Wiese - … and analgesia: The fifth edition of …, 2015 - Wiley Online Library
Opioids are the prototypical analgesics, antitussives, and antidiarrheal drug class. The
opioid receptor system or opioid effects have been identified in numerous animal species …

Applying biopharmaceutical classification system (BCS) criteria to predict oral absorption of drugs in dogs: challenges and pitfalls

MG Papich, MN Martinez - The AAPS journal, 2015 - Springer
Abstract The Biopharmaceutical Classification System (BCS) has been a prognostic tool for
assessing the potential effects of formulation on the human drug oral bioavailability. When …

Lack of effectiveness of tramadol hydrochloride for the treatment of pain and joint dysfunction in dogs with chronic osteoarthritis

SC Budsberg, BT Torres, SA Kleine… - Journal of the …, 2018 - Am Vet Med Assoc
Lack of effectiveness of tramadol hydrochloride for the treatment of pain and joint
dysfunction in dogs with chronic osteoarthritis in: Journal of the American Veterinary …

Outpatient oral analgesics in dogs and cats beyond nonsteroidal antiinflammatory drugs: an evidence-based approach

B KuKanich - Veterinary Clinics: Small Animal Practice, 2013 - vetsmall.theclinics.com
Treatment of outpatient pain in dogs and cats can be rewarding for the owners and
veterinarians. Nonsteroidal antiinflammatory drugs (NSAIDs) are commonly administered to …

Effect of analgesic therapy on clinical outcome measures in a randomized controlled trial using client-owned dogs with hip osteoarthritis

S Malek, SJ Sample, Z Schwartz, B Nemke… - BMC veterinary …, 2012 - Springer
Background Pain and impaired mobility because of osteoarthritis (OA) is common in dogs
and humans. Efficacy studies of analgesic drug treatment of dogs with naturally occurring …

Tramadol metabolism to O-desmethyl tramadol (M1) and N-desmethyl tramadol (M2) by dog liver microsomes: species comparison and identification of responsible …

TE Perez, KL Mealey, TL Grubb, SA Greene… - Drug Metabolism and …, 2016 - Elsevier
Tramadol is widely used to manage mild to moderately painful conditions in dogs. However,
this use is controversial, since clinical efficacy studies in dogs showed conflicting results …

Effects of tramadol alone, in combination with meloxicam or dipyrone, on postoperative pain and the analgesic requirement in dogs undergoing unilateral mastectomy …

RCR Teixeira, ER Monteiro, D Campagnol… - Veterinary anaesthesia …, 2013 - Elsevier
Objective To compare the effects of tramadol alone, or in combination with dipyrone or
meloxicam, on postoperative pain and analgesia requirement after unilateral mastectomy …