Onset of many forms of epilepsy occurs after an initial epileptogenic insult or as a result of an
identified genetic defect. Given that the precipitating insult is known, these epilepsies are, in …

Epilepsy is a common and serious neurological disorder characterised by recurrent
spontaneous seizures. Frontline pharmacotherapy includes small-molecule antiseizure …

Post-traumatic epilepsy (PTE) is one of the most devastating long-term, network
consequences of traumatic brain injury (TBI). There is currently no approved treatment that …

Epilepsy is the result of a group of transient abnormalities in brain function caused by an
abnormal, highly synchronized discharge of brain neurons. MicroRNA (miRNA) is a class of …

Temporal lobe epilepsy is the most common form of focal epilepsy in adults, accounting for
one third of all diagnosed epileptic patients, with seizures originating from or involving …

Over decades, the prevailing standard in drug discovery was the concept of designing highly
selective compounds that act on individual drug targets. However, more recently, multi-target …

Epilepsy is a highly prevalent neurological disorder, affecting between 5–8 per 1000
individuals and is associated with a lifetime risk of up to 3%. In addition to high incidence …

The use of easily accessible peripheral samples, such as blood or saliva, to investigate
neurological and neuropsychiatric disorders is well-established in genetic and epigenetic …

Epilepsy frequently develops as a result of brain insult; however, there are no tools allowing
to predict which patients suffering from trauma will eventually develop epilepsy. microRNAs …

Epilepsy is a neurological disorder that impacts millions of people worldwide, and it is
characterized by the occurrence of recurrent seizures. The pathogenesis of epilepsy is …