From animal models to human individuality: Integrative approaches to the study of brain plasticity

M Hille, S Kühn, G Kempermann, T Bonhoeffer… - Neuron, 2024 - cell.com
Plasticity allows organisms to form lasting adaptive changes in neural structures in response
to interactions with the environment. It serves both species-general functions and …

Neurobiological mechanisms of electroconvulsive therapy for depression: Insights into hippocampal volumetric increases from clinical and preclinical studies

Y Abe, VJ Erchinger, OT Ousdal… - Journal of …, 2024 - Wiley Online Library
Depression is a highly prevalent and disabling psychiatric disorder. The hippocampus,
which plays a central role in mood regulation and memory, has received considerable …

Cellular correlates of gray matter volume changes in magnetic resonance morphometry identified by two-photon microscopy

L Asan, C Falfan-Melgoza, CA Beretta, M Sack… - Scientific Reports, 2021 - nature.com
Magnetic resonance imaging (MRI) of the brain combined with voxel-based morphometry
(VBM) revealed changes in gray matter volume (GMV) in various disorders. However, the …

Hippocampal blood flow abnormality associated with depressive symptoms and cognitive impairment in patients with chronic heart failure

H Suzuki, Y Matsumoto, H Ota, K Sugimura… - Circulation …, 2016 - jstage.jst.go.jp
Background: Depressive symptoms and memory impairment are prevalent in patients with
chronic heart failure (CHF). Although the mechanisms remain to be elucidated, the …

Abnormal brain white matter microstructure is associated with both pre-hypertension and hypertension

H Suzuki, H Gao, W Bai, E Evangelou, B Glocker… - PLoS …, 2017 - journals.plos.org
Objectives To characterize effects of chronically elevated blood pressure on the brain, we
tested for brain white matter microstructural differences associated with normotension, pre …

Theanine, the main amino acid in tea, prevents stress-induced brain atrophy by modifying early stress responses

K Unno, A Sumiyoshi, T Konishi, M Hayashi, K Taguchi… - Nutrients, 2020 - mdpi.com
Chronic stress can impair the health of human brains. An important strategy that may prevent
the accumulation of stress may be the consumption of functional foods. When senescence …

Regional gray matter volume increases following 7 days of voluntary wheel running exercise: a longitudinal VBM study in rats

A Sumiyoshi, Y Taki, H Nonaka, H Takeuchi… - Neuroimage, 2014 - Elsevier
The effects of physical exercise on brain morphology in rodents have been well documented
in histological studies. However, to further understand when and where morphological …

Brain atrophy in the visual cortex and thalamus induced by severe stress in animal model

T Yoshii, N Oishi, K Ikoma, I Nishimura, Y Sakai… - Scientific reports, 2017 - nature.com
Psychological stress induces many diseases including post-traumatic stress disorder
(PTSD); however, the causal relationship between stress and brain atrophy has not been …

Cell therapies for autism spectrum disorder based on new pathophysiology: A review

M Nabetani, T Mukai, A Taguchi - Cell Transplantation, 2023 - journals.sagepub.com
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized
by difficulties in social communication, repetitive behaviors, and restricted interests, with …

Regional brain shrinkage over two years: individual differences and effects of pro-inflammatory genetic polymorphisms

N Persson, P Ghisletta, CL Dahle, AR Bender, Y Yang… - Neuroimage, 2014 - Elsevier
We examined regional changes in brain volume in healthy adults (N= 167, age 19–79 years
at baseline; N= 90 at follow-up) over approximately two years. With latent change score …