Phage therapy—challenges, opportunities and future prospects

B Zalewska-Piątek - Pharmaceuticals, 2023 - mdpi.com
The increasing drug resistance of bacteria to commonly used antibiotics creates the need to
search for and develop alternative forms of treatment. Phage therapy fits this trend perfectly …

[HTML][HTML] Beyond antibiotics: what the future holds

P Benyamini - Antibiotics, 2024 - mdpi.com
The prevalence of multidrug resistance (MDR) and stagnant drug-development pipelines
have led to the rapid rise of hard-to-treat antibiotic-resistant bacterial infections. These …

Synergistic effects of bacteriophage cocktail and antibiotics combinations against extensively drug-resistant Acinetobacter baumannii

S Rastegar, M Skurnik, O Tadjrobehkar… - BMC Infectious …, 2024 - Springer
Background The extensively drug-resistant (XDR) strains of Acinetobacter baumannii have
become a major cause of nosocomial infections, increasing morbidity and mortality …

The potential use of bacteriophages as antibacterial agents against Klebsiella pneumoniae

O Gholizadeh, HEG Ghaleh, M Tat, R Ranjbar… - Virology Journal, 2024 - Springer
One of the most common bacteria that cause nosocomial infections is Klebsiella pneumonia
(K. pneumoniae), especially in patients who are very sick and admitted to the intensive care …

Bacteriophage therapy in musculoskeletal infections: from basic science to clinical application

T Ferry, J Onsea, T Roussel-Gaillard… - EFORT Open …, 2024 - eor.bioscientifica.com
The treatment of musculoskeletal infections (MSIs), including periprosthetic joint infection
(PJI) and fracture-related infection (FRI), is often complicated by biofilm-related challenges …

Cationic Porphyrins as Antimicrobial and Antiviral Agents in Photodynamic Therapy

IO Savelyeva, KA Zhdanova, MA Gradova… - Current Issues in …, 2023 - mdpi.com
Antimicrobial photodynamic therapy (APDT) has received a great deal of attention due to its
unique ability to kill all currently known classes of microorganisms. To date, infectious …

Screening of Hydrophilic Polymers Reveals Broad Activity in Protecting Phages during Cryopreservation

HL Marton, A Bhatt, AP Sagona, P Kilbride… - …, 2023 - ACS Publications
Bacteriophages have many biotechnological and therapeutic applications, but as with other
biologics, cryopreservation is essential for storage and distribution. Macromolecular …

A mini-review on the role of bacteriophages in food safety

N Amjad, MS Naseer, A Imran, SV Menon… - CyTA-Journal of …, 2024 - Taylor & Francis
Despite their serious disadvantages, which include higher upfront costs, the possibility of
malfunctions due to corrosiveness, and a negative impact on the organoleptic properties of …

[HTML][HTML] Exploring the Bacteriophage Frontier: A Bibliometric Analysis of Clinical Trials Between 1965 and 2024

N Dagli, M Haque, S Kumar - Cureus, 2024 - ncbi.nlm.nih.gov
In recent years, the rise of antibiotic-resistant bacteria has posed a severe threat to global
public health, necessitating innovative and alternative approaches to combat this escalating …

Phage Delivery Strategies for Biocontrolling Human, Animal, and Plant Bacterial Infections: State of the Art

MMDC Vila, LMN Balcão, VM Balcão - Pharmaceutics, 2024 - mdpi.com
This review aims at presenting the main strategies that are currently available for the
delivery of bacteriophages to combat bacterial infections in humans, animals, and plants. It …