Early detection of cancer

D Crosby, S Bhatia, KM Brindle, LM Coussens, C Dive… - Science, 2022 - science.org
Survival improves when cancer is detected early. However,~ 50% of cancers are at an
advanced stage when diagnosed. Early detection of cancer or precancerous change allows …

The future of early cancer detection

RC Fitzgerald, AC Antoniou, L Fruk, N Rosenfeld - Nature medicine, 2022 - nature.com
A proactive approach to detecting cancer at an early stage can make treatments more
effective, with fewer side effects and improved long-term survival. However, as detection …

[HTML][HTML] Prostate cancer screening with PSA and MRI followed by targeted biopsy only

J Hugosson, M Månsson, J Wallström… - … England Journal of …, 2022 - Mass Medical Soc
Background Screening for prostate cancer is burdened by a high rate of overdiagnosis. The
most appropriate algorithm for population-based screening is unknown. Methods We invited …

Epidemiology and prevention of prostate cancer

G Gandaglia, R Leni, F Bray, N Fleshner… - European urology …, 2021 - Elsevier
Abstract Context Worldwide, prostate cancer (PCa) represents the second most common
solid tumor in men. Objective To assess the geographical distribution of PCa …

[HTML][HTML] MRI-targeted or standard biopsy in prostate cancer screening

M Eklund, F Jäderling, A Discacciati… - New England journal …, 2021 - Mass Medical Soc
Background High rates of overdiagnosis are a critical barrier to organized prostate cancer
screening. Magnetic resonance imaging (MRI) with targeted biopsy has shown the potential …

EAU-EANM-ESTRO-ESUR-SIOG guidelines on prostate cancer—2020 update. Part 1: screening, diagnosis, and local treatment with curative intent

N Mottet, RCN van den Bergh, E Briers… - European urology, 2021 - Elsevier
Objective To present a summary of the 2020 version of the European Association of Urology
(EAU)-European Association of Nuclear Medicine (EANM)-European Society for …

Early detection of prostate cancer: AUA/SUO guideline part I: prostate cancer screening

JT Wei, D Barocas, S Carlsson, F Coakley… - Journal of …, 2023 - journals.lww.com
Purpose: The summary presented herein covers recommendations on the early detection of
prostate cancer and provides a framework to facilitate clinical decision-making in the …

Prostate-specific antigen testing as part of a risk-adapted early detection strategy for prostate cancer: European Association of Urology position and recommendations …

H Van Poppel, MJ Roobol, CR Chapple, JWF Catto… - European Urology, 2021 - Elsevier
Background Recommendations against prostate-specific antigen (PSA) testing in 2012 have
increased advanced-stage diagnosis and prostate cancer–specific mortality rates. Objective …

Epidemiology and genomics of prostate cancer in Asian men

Y Zhu, M Mo, Y Wei, J Wu, J Pan, SJ Freedland… - Nature Reviews …, 2021 - nature.com
Prostate cancer is a global health problem, but incidence varies considerably across
different continents. Asia is traditionally considered a low-incidence area, but the incidence …

Serum PSA-based early detection of prostate cancer in Europe and globally: past, present and future

H Van Poppel, T Albreht, P Basu, R Hogenhout… - Nature Reviews …, 2022 - nature.com
In the pre-PSA-detection era, a large proportion of men were diagnosed with metastatic
prostate cancer and died of the disease; after the introduction of the serum PSA test …