The formation of the digits is a tightly regulated process. During embryogenesis, disturbance
of genetic pathways in limb development could result in syndactyly; a common congenital …

Suppl 1: The Epidemiology, Genetics and Future Management of Syndactyly - PMC Back to
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Disorders that result from de-arrangement of growth, development and/or differentiation of
the appendages (limbs and digit) are collectively called as inherited abnormalities of human …

Background Syndactyly type 1 (SD1) is an autosomal dominant limb malformation
characterized in its classical form by complete or partial webbing between the third and …

Syndactyly, webbing of adjacent digits with or without bony fusion, is one of the most
common hereditary limb malformations. It occurs either as an isolated abnormality or as a …

There is good evidence from the medical literature that type I syndactyly, the most common
form of the nonsyndromic syndactylies, is clinically heterogeneous. We therefore propose to …

Previously we have described a novel and distinct form of non‐syndromic osseous
syndactyly segregating in an autosomal recessive pattern in a consanguineous Pakistani …

ABSTRACT Syndactyly (Syn= together; Dactylos= digits) is the most common limb defect
mostly characterized by webbing of digits. It may be webbing with or without bony fusion and …

Non‐syndromic syndactylies have been classified into five major types (I–V), all showing
autosomal dominant mode of inheritance. Later, the classification was extended and three …

Background FU is the human homologue of the Drosophila gene fused whose product fused
is a positive regulator of the transcription factor Cubitus interruptus (Ci). Thus, FU may act as …