Description Nonalcoholic fatty liver disease (NAFLD) is well recognized as a leading
etiology for chronic liver disease, affecting> 25% of the US and global populations. Up to 1 …

Non-alcoholic fatty liver disease (NAFLD) is one of the most frequent causes of chronic liver
disease in the Western world, probably due to the growing prevalence of obesity, metabolic …

Background & Aims Hepatocellular carcinoma (HCC) risk stratification in individuals with
dysmetabolism is a major unmet need. Genetic predisposition contributes to non-alcoholic …

Background & Aims There is substantial inter-individual variability in the risk of non-alcoholic
fatty liver disease (NAFLD). Part of which is explained by insulin resistance (IR)('MetComp') …

Non-alcoholic fatty liver disease (NAFLD) is characterized by the accumulation of fat in more
than 5% of hepatocytes in the absence of excessive alcohol consumption and other …

Background and Aims We hypothesized that a genetic risk score (GRS) for fatty liver disease
influences the risk of cirrhosis and hepatocellular carcinoma (HCC). Three genetic variants …

Abstract 17β-hydroxysteroid dehydrogenase-13 is a hepatocyte-specific, lipid droplet-
associated protein. A common loss-of-function variant of HSD17B13 (rs72613567: TA) …

Background Non‐alcoholic steatohepatitis (NASH) is a severe form of non‐alcoholic fatty
liver disease (NAFLD) characterised by liver fat accumulation, inflammation and progressive …

Nonalcoholic fatty liver disease (NAFLD) represents a burgeoning worldwide epidemic
whose etiology reflects multiple interactions between environmental and genetic factors …

Excess liver fat, called hepatic steatosis, is a leading risk factor for end-stage liver disease
and cardiometabolic diseases but often remains undiagnosed in clinical practice because of …