Hepatocellular carcinoma (HCC): Epidemiology, etiology and molecular classification
S Chidambaranathan-Reghupaty, PB Fisher… - Advances in cancer …, 2021 - Elsevier
Hepatocellular carcinoma (HCC), the primary malignancy of hepatocytes, is a diagnosis with
bleak outcome. According to National Cancer Institute's SEER database, the average five …
bleak outcome. According to National Cancer Institute's SEER database, the average five …
The omniscient placenta: metabolic and epigenetic regulation of fetal programming
Fetal development could be considered a sensitive period wherein exogenous insults and
changes to the maternal milieu can have long-term impacts on developmental programming …
changes to the maternal milieu can have long-term impacts on developmental programming …
MicroRNA-223 coordinates cholesterol homeostasis
KC Vickers, SR Landstreet, MG Levin… - Proceedings of the …, 2014 - National Acad Sciences
MicroRNAs (miRNAs) regulate a wide variety of biological processes and contribute to
metabolic homeostasis. Here, we demonstrate that microRNA-223 (miR-223), an miRNA …
metabolic homeostasis. Here, we demonstrate that microRNA-223 (miR-223), an miRNA …
[HTML][HTML] Hepatocellular carcinoma: causes, mechanism of progression and biomarkers
Hepatocellular Carcinoma (HCC) is one of the most common malignant tumours in the
world. It is a heterogeneous group of a tumour that vary in risk factor and genetic and …
world. It is a heterogeneous group of a tumour that vary in risk factor and genetic and …
Epigenetics and microRNAs in cancer
A Ramassone, S Pagotto, A Veronese… - International journal of …, 2018 - mdpi.com
The ability to reprogram the transcriptional circuitry by remodeling the three-dimensional
structure of the genome is exploited by cancer cells to promote tumorigenesis. This …
structure of the genome is exploited by cancer cells to promote tumorigenesis. This …
The genetic and epigenetic alterations in human hepatocellular carcinoma: a recent update
Hepatocellular carcinoma (HCC) is one of the most frequent human malignancies worldwide
with very poor prognosis. It is generally accepted that the progression of HCC is a long-term …
with very poor prognosis. It is generally accepted that the progression of HCC is a long-term …
Micro RNA‐145: a potent tumour suppressor that regulates multiple cellular pathways
SY Cui, R Wang, LB Chen - Journal of cellular and molecular …, 2014 - Wiley Online Library
Micro RNA s are endogenous, small (18–25 nucleotides) non‐coding RNA s, which regulate
genes expression by directly binding to the 3′‐untranslated regions of the target …
genes expression by directly binding to the 3′‐untranslated regions of the target …
[HTML][HTML] hsa_circ_0001955 enhances in vitro proliferation, migration, and invasion of HCC cells through miR-145-5p/NRAS axis
B Ding, W Fan, W Lou - Molecular Therapy-Nucleic Acids, 2020 - cell.com
Increasing circular RNAs (circRNAs) have been reported to act as key players in human
malignancies. However, the expression, role, and mechanism of circRNAs in HCC are not …
malignancies. However, the expression, role, and mechanism of circRNAs in HCC are not …
miR-145 antagonizes SNAI1-mediated stemness and radiation resistance in colorectal cancer
Y Zhu, C Wang, SA Becker, K Hurst, LM Nogueira… - Molecular Therapy, 2018 - cell.com
Epithelial-to-mesenchymal transition (EMT) has been closely linked with therapy resistance
and cancer stem cells (CSCs). However, EMT pathways have proven challenging to …
and cancer stem cells (CSCs). However, EMT pathways have proven challenging to …
Histone deacetylase 2 selective inhibitors: a versatile therapeutic strategy as next generation drug target in cancer therapy
Acetylation and deacetylation of histone and several non-histone proteins are the two
important processes amongst the different modes of epigenetic modulation that are involved …
important processes amongst the different modes of epigenetic modulation that are involved …