PLA short sub-micron fiber reinforcement of 3D bioprinted alginate constructs for cartilage regeneration
A Kosik-Kozioł, M Costantini, T Bolek, K Szöke… - …, 2017 - iopscience.iop.org
In this study, we present an innovative strategy to reinforce 3D-printed hydrogel constructs
for cartilage tissue engineering by formulating composite bioinks containing alginate and …
for cartilage tissue engineering by formulating composite bioinks containing alginate and …
Chondrogenesis in a hyaluronic acid scaffold: comparison between chondrocytes and MSC from bone marrow and adipose tissue
RB Jakobsen, A Shahdadfar, FP Reinholt… - Knee Surgery, Sports …, 2010 - Springer
Abstract Treatment of focal lesions of the articular cartilage of the knee using chondrocytes
in a hyaluronic acid (HA) scaffold is already being investigated in clinical trials. An …
in a hyaluronic acid (HA) scaffold is already being investigated in clinical trials. An …
Similar properties of chondrocytes from osteoarthritis joints and mesenchymal stem cells from healthy donors for tissue engineering of articular cartilage
AM Fernandes, SR Herlofsen, TA Karlsen, AM Küchler… - PloS one, 2013 - journals.plos.org
Lesions of hyaline cartilage do not heal spontaneously, and represent a therapeutic
challenge. In vitro engineering of articular cartilage using cells and biomaterials may prove …
challenge. In vitro engineering of articular cartilage using cells and biomaterials may prove …
Human primary articular chondrocytes, chondroblasts-like cells, and dedifferentiated chondrocytes: differences in gene, microRNA, and protein expression and …
TA Karlsen, A Shahdadfar… - Tissue Engineering Part C …, 2011 - liebertpub.com
In this study we have isolated human primary uncultured articular chondrocytes. When these
cells are allowed to proliferate within their own extracellular matrix (ECM), they begin to …
cells are allowed to proliferate within their own extracellular matrix (ECM), they begin to …
Chondrocytes expressing intracellular collagen type II enter the cell cycle and co‐express collagen type I in monolayer culture
A Tekari, R Luginbuehl, W Hofstetter… - Journal of orthopaedic …, 2014 - Wiley Online Library
For autologous chondrocyte transplantation, articular chondrocytes are harvested from
cartilage tissue and expanded in vitro in monolayer culture. We aimed to characterize with a …
cartilage tissue and expanded in vitro in monolayer culture. We aimed to characterize with a …
Development of 4-hydroxyproline analysis kit and its application to collagen quantification
YK Lin, CY Kuan - Food chemistry, 2010 - Elsevier
4-Hydroxyproline (4-Hyp) is a specific amino acid of collagen and widely used as a factor to
estimate the collagen content in biological specimens. The authors have developed an …
estimate the collagen content in biological specimens. The authors have developed an …
Autologous chondrocyte implantation to repair knee cartilage injury: ultrastructural evaluation at 2 years and long-term follow-up including muscle strength …
S Løken, TC Ludvigsen, T Høysveen, I Holm… - Knee Surgery, Sports …, 2009 - Springer
Autologous chondrocyte implantation (ACI) usually results in improvement in clinical scores.
However, long-term isokinetic muscle strength measurements have not been reported …
However, long-term isokinetic muscle strength measurements have not been reported …
Macromolecular crowding as a means to assess the effectiveness of chondrogenic media
V Graceffa, DI Zeugolis - Journal of Tissue Engineering and …, 2019 - Wiley Online Library
Chondrocyte‐based tissue engineering requires in vitro cell expansion, which is associated
with phenotypic losses, decrease in Collagen Type II synthesis and increase in Collagen …
with phenotypic losses, decrease in Collagen Type II synthesis and increase in Collagen …
Synoviocyte derived-extracellular matrix enhances human articular chondrocyte proliferation and maintains re-differentiation capacity at both low and atmospheric …
Background Current tissue engineering methods are insufficient for total joint resurfacing,
and chondrocytes undergo de-differentiation when expanded on tissue culture plastic. De …
and chondrocytes undergo de-differentiation when expanded on tissue culture plastic. De …
Enhanced chondrogenic marker expression of human mesenchymal stem cells by interaction with both TGF‐β3 and hyaluronic acid
SH Bhang, JY Jeon, WG La, JY Seong… - Biotechnology and …, 2011 - Wiley Online Library
This study was designed to evaluate the additive effects of transforming growth factor‐beta3
(TGF‐β3) and hyaluronic acid (HA) on chondrogenic differentiation of human mesenchymal …
(TGF‐β3) and hyaluronic acid (HA) on chondrogenic differentiation of human mesenchymal …